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Sean D. Murphy
Researcher at Howard Hughes Medical Institute
Publications - 11
Citations - 4282
Sean D. Murphy is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Shotgun sequencing & Biological neural network. The author has an hindex of 10, co-authored 11 publications receiving 3827 citations. Previous affiliations of Sean D. Murphy include Celera Corporation & J. Craig Venter Institute.
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Journal ArticleDOI
The Genome Sequence of the Malaria Mosquito Anopheles gambiae
Robert A. Holt,G. Mani Subramanian,Aaron L. Halpern,Granger G. Sutton,Rosane Charlab,Deborah R. Nusskern,Patrick Wincker,Andrew G. Clark,José M. C. Ribeiro,Ron Wides,Steven L. Salzberg,Brendan J. Loftus,Mark Yandell,William H. Majoros,William H. Majoros,Douglas B. Rusch,Zhongwu Lai,Cheryl L. Kraft,Josep F. Abril,Véronique Anthouard,Peter Arensburger,Peter W. Atkinson,Holly Baden,Véronique de Berardinis,Danita Baldwin,Vladimir Benes,Jim Biedler,Claudia Blass,Randall Bolanos,Didier Boscus,Mary Barnstead,Shuang Cai,Kabir Chatuverdi,George K. Christophides,Mathew A. Chrystal,Michele Clamp,Anibal Cravchik,Val Curwen,Ali N Dana,Arthur L. Delcher,Ian M. Dew,Cheryl A. Evans,Michael Flanigan,Anne Grundschober-Freimoser,Lisa Friedli,Zhiping Gu,Ping Guan,Roderic Guigó,Maureen E. Hillenmeyer,Susanne L. Hladun,James R. Hogan,Young S. Hong,Jeffrey Hoover,Olivier Jaillon,Zhaoxi Ke,Zhaoxi Ke,Chinnappa D. Kodira,Kokoza Eb,Anastasios C. Koutsos,Ivica Letunic,Alex Levitsky,Yong Liang,Jhy-Jhu Lin,Jhy-Jhu Lin,Neil F. Lobo,John Lopez,Joel A. Malek,Tina C. McIntosh,Stephan Meister,Jason R. Miller,Clark M. Mobarry,Emmanuel Mongin,Sean D. Murphy,David A. O'Brochta,Cynthia Pfannkoch,Rong Qi,Megan A. Regier,Karin A. Remington,Hongguang Shao,Maria V. Sharakhova,Cynthia Sitter,Jyoti Shetty,Thomas J. Smith,Renee Strong,Jingtao Sun,Dana Thomasova,Lucas Q. Ton,Pantelis Topalis,Zhijian Tu,Maria F. Unger,Brian P. Walenz,Aihui Wang,Jian Wang,Mei Wang,X. Wang,Kerry J. Woodford,Jennifer R. Wortman,Jennifer R. Wortman,Martin Wu,Alison Yao,Evgeny M. Zdobnov,Hongyu Zhang,Qi Zhao,Shaying Zhao,Shiaoping C. Zhu,Igor F. Zhimulev,Mario Coluzzi,Alessandra della Torre,Charles Roth,Christos Louis,Francis Kalush,Richard J. Mural,Eugene W. Myers,Mark Raymond Adams,Hamilton O. Smith,Samuel Broder,Malcolm J. Gardner,Claire M. Fraser,Ewan Birney,Peer Bork,Paul T. Brey,J. Craig Venter,J. Craig Venter,Jean Weissenbach,Fotis C. Kafatos,Frank H. Collins,Stephen L. Hoffman +126 more
TL;DR: Analysis of the PEST strain of A. gambiae revealed strong evidence for about 14,000 protein-encoding transcripts, and prominent expansions in specific families of proteins likely involved in cell adhesion and immunity were noted.
Journal ArticleDOI
A GAL4-Driver Line Resource for Drosophila Neurobiology
Arnim Jenett,Gerald M. Rubin,Teri-T B. Ngo,David Shepherd,Christine Murphy,Heather Dionne,Barret D. Pfeiffer,Amanda Cavallaro,Donald Hall,Jennifer Jeter,Nirmala Iyer,Dona Fetter,Joanna H. Hausenfluck,Hanchuan Peng,Eric T. Trautman,Robert Svirskas,Eugene W. Myers,Zbigniew R. Iwinski,Yoshinori Aso,Gina M. DePasquale,Adrianne Enos,Phuson Hulamm,S. Lam,Hsing-Hsi Li,Todd R. Laverty,Fuhui Long,Lei Qu,Sean D. Murphy,Konrad Rokicki,Todd Safford,Kshiti Shaw,Julie H. Simpson,Allison Sowell,Susana Tae,Yang Yu,Christopher T. Zugates +35 more
TL;DR: The utility of 7,000 transgenic lines of Drosophila melanogaster for identifying novel neuronal cell types, revealing brain asymmetry, and describing the nature and extent of neuronal shape stereotypy is illustrated.
Journal ArticleDOI
A Comparison of Whole-Genome Shotgun-Derived Mouse Chromosome 16 and the Human Genome
Richard J. Mural,Mark Raymond Adams,Eugene W. Myers,Hamilton O. Smith,George L. Gabor Miklos,Ron Wides,Aaron L. Halpern,Peter W. Li,Granger G. Sutton,J. H. Nadeau,Steven L. Salzberg,Robert A. Holt,Chinnappa D. Kodira,Fu Lu,Lin Chen,Zuoming Deng,Carlos Evangelista,Weiniu Gan,Thomas J. Heiman,Jiayin Li,Zhenya Li,Gennady V. Merkulov,Natalia Milshina,Ashwinikumar K Naik,Rong Qi,Bixiong Chris Shue,Aihui Wang,Jian Wang,Xin Wang,Xianghe Yan,Jane Ye,Shibu Yooseph,Qi Zhao,Liansheng Zheng,Shiaoping C. Zhu,Kendra Biddick,Randall Bolanos,Arthur L. Delcher,Ian M. Dew,Daniel Fasulo,Michael Flanigan,Daniel H. Huson,Saul A. Kravitz,Jason R. Miller,Clark M. Mobarry,Knut Reinert,Karin A. Remington,Qing Zhang,Xiangqun H. Zheng,Deborah R. Nusskern,Zhongwu Lai,Yiding Lei,Wenyan Zhong,Alison Yao,Ping Guan,Rui-Ru Ji,Zhiping Gu,Zhen-Yuan Wang,Fei Zhong,Chunlin Xiao,Chia-Chien Chiang,Mark Yandell,Jennifer R. Wortman,Peter Amanatides,Suzanne Hladun,Eric Pratts,Jeffery Johnson,Kristina Dodson,Kerry J. Woodford,Cheryl A. Evans,Barry Gropman,Douglas B. Rusch,Eli Venter,Mei Wang,Thomas J. Smith,Jarrett Houck,Donald E. Tompkins,Charles Haynes,Debbie Jacob,Soo H. Chin,David R. Allen,Carl Dahlke,Robert Sanders,Kelvin Li,Xiangjun Liu,Alexander Levitsky,William H. Majoros,Quan Chen,Ashley Xia,John Lopez,Michael Donnelly,Matthew Newman,A. Glodek,Cheryl L. Kraft,Marc Nodell,Feroze Ali,Huijin An,Danita Baldwin-Pitts,Karen Beeson,Shuang Cai,Mark Carnes,Amy Carver,Parris Caulk,Yen-Hui Chen,Ming-Lai Cheng,My Coyne,Michelle Crowder,Steven Danaher,Lionel Davenport,Raymond Desilets,Susanne Dietz,Lisa Doup,Patrick Dullaghan,Steven Ferriera,Carl Fosler,Harold Gire,Andres Gluecksmann,Jeannine D. Gocayne,Jonathan Gray,Brit J. Hart,Jason Haynes,Jeffery Hoover,Tim Howland,Chinyere Ibegwam,Mena Jalali,David Johns,Leslie Kline,Daniel S. Ma,Steven MacCawley,Anand Magoon,Felecia Mann,David May,Tina C. McIntosh,Somil Mehta,Linda Moy,Mee Moy,Brian Murphy,Sean D. Murphy,Keith Nelson,Zubeda Nuri,Kimberly A. Parker,Alexandre C. Prudhomme,Vinita Puri,Hina Qureshi,John C. Raley,Matthew Reardon,Megan A. Regier,Yu-Hui Rogers,Deanna Romblad,Jakob Schutz,Richard Scott,Cynthia Sitter,Michella Smallwood,Arlan Sprague,Erin Stewart,Renee Strong,Ellen Suh,Karena Sylvester,Reginald Thomas,Ni Ni Tint,Christopher Tsonis,Gary Wang,George Wang,Monica Williams,Sherita Williams,Sandra Windsor,Keriellen Wolfe,Mitchell Wu,Jayshree Zaveri,Kabir Chaturvedi,Andrei Gabrielian,Zhaoxi Ke,Jingtao Sun,Gangadharan Subramanian,J. Craig Venter +174 more
TL;DR: Comparison of the structure and protein-coding potential of Mmu 16 with that of the homologous segments of the human genome identifies regions of conserved synteny with human chromosomes (Hsa) 3, 8, 12, 16, 21, and 22.
Journal ArticleDOI
Reconstruction of 1,000 Projection Neurons Reveals New Cell Types and Organization of Long-Range Connectivity in the Mouse Brain
Johan Winnubst,Erhan Bas,Tiago Ferreira,Zhuhao Wu,Michael N. Economo,Patrick Edson,Ben J. Arthur,Christopher M. Bruns,Konrad Rokicki,David Schauder,Donald J. Olbris,Sean D. Murphy,David G. Ackerman,Cameron Arshadi,Perry Baldwin,Regina Blake,Ahmad Elsayed,Mashtura Hasan,Daniel Ramirez,Bruno Dos Santos,Monet Weldon,Amina Zafar,Joshua T. Dudman,Charles R. Gerfen,Adam W. Hantman,Wyatt Korff,Scott M. Sternson,Nelson Spruston,Karel Svoboda,Jayaram Chandrashekar +29 more
TL;DR: A robust and efficient platform for imaging and reconstructing complete neuronal morphologies, including axonal arbors that span substantial portions of the brain are presented and axonal shapes revealed previously unknown subtypes of projection neurons and suggest organizational principles of long-range connectivity.
Journal ArticleDOI
A Standard MIGS/MIMS Compliant XML Schema: Toward the Development of the Genomic Contextual Data Markup Language (GCDML)
Renzo Kottmann,Tanya Gray,Sean D. Murphy,Leonid Kagan,Saul A. Kravitz,Thierry Lombardot,Dawn Field,Frank Oliver Glöckner +7 more
TL;DR: The need for a sample-centric, strongly-typed schema, which will provide a diverse set of descriptors for describing the exact origin and processing of a biological sample, from sampling to sequencing, and subsequent analysis is described.