Institution
Fukushima University
Education•Fukushima, Japan•
About: Fukushima University is a education organization based out in Fukushima, Japan. It is known for research contribution in the topics: Population & Environmental science. The organization has 705 authors who have published 1748 publications receiving 22358 citations.
Topics: Population, Environmental science, Dark energy, Sediment, Soil water
Papers published on a yearly basis
Papers
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Federal Urdu University1, Columbia University2, Woods Hole Oceanographic Institution3, Addis Ababa University4, Indian Institute of Tropical Meteorology5, University of Trieste6, Swiss Federal Institute for Forest, Snow and Landscape Research7, University of Montpellier8, University of Bergen9, University of Chile10, Austral University of Chile11, University of Tasmania12, Australian Antarctic Division13, National Oceanic and Atmospheric Administration14, University of Mainz15, Xishuangbanna Tropical Botanical Garden16, Nepal Academy of Science and Technology17, Chinese Academy of Sciences18, University of Melbourne19, Complutense University of Madrid20, Université catholique de Louvain21, University of the Witwatersrand22, Hydrologic Research Center23, University of Bern24, University of Helsinki25, Northern Arizona University26, Fukushima University27, Stockholm University28, Université Paris-Saclay29, National Institute of Water and Atmospheric Research30, University of Giessen31, Swansea University32, Desert Research Institute33, National Scientific and Technical Research Council34, British Antarctic Survey35, Nagoya University36, University of Brighton37, Florida State University38, Alfred Wegener Institute for Polar and Marine Research39, University of Exeter40, University of New South Wales41, Centro de Estudios Científicos42, University of Florence43, University of Texas at Austin44, Russian Academy of Sciences45, University of Washington46, National Centre for Antarctic and Ocean Research47, University of Arizona48, Ghent University49, University of Ottawa50, University of Copenhagen51, University of Colorado Boulder52, Shinshu University53
TL;DR: The authors reconstructed past temperatures for seven continental-scale regions during the past one to two millennia and found that the most coherent feature in nearly all of the regional temperature reconstructions is a long-term cooling trend, which ended late in the nineteenth century.
Abstract: Past global climate changes had strong regional expression To elucidate their spatio-temporal pattern, we reconstructed past temperatures for seven continental-scale regions during the past one to two millennia The most coherent feature in nearly all of the regional temperature reconstructions is a long-term cooling trend, which ended late in the nineteenth century At multi-decadal to centennial scales, temperature variability shows distinctly different regional patterns, with more similarity within each hemisphere than between them There were no globally synchronous multi-decadal warm or cold intervals that define a worldwide Medieval Warm Period or Little Ice Age, but all reconstructions show generally cold conditions between ad 1580 and 1880, punctuated in some regions by warm decades during the eighteenth century The transition to these colder conditions occurred earlier in the Arctic, Europe and Asia than in North America or the Southern Hemisphere regions Recent warming reversed the long-term cooling; during the period ad 1971–2000, the area-weighted average reconstructed temperature was higher than any other time in nearly 1,400 years
885 citations
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TL;DR: It is revealed that orexin neurons receive input from several brain areas, including the amygdala, basal forebrain cholinergic neurons, GABAergic neuron in the preoptic area, and serotonergic neurons in the median/paramedian raphe nuclei.
435 citations
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TL;DR: A pH-phased two-stage fermentation process combined thermophilic hydrogen production and mesophilic methane production with recirculation of the digested sludge was suggested in this paper.
292 citations
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Katholieke Universiteit Leuven1, Fukushima University2, University of Oxford3, Ludwig Maximilian University of Munich4, University of Texas MD Anderson Cancer Center5, University of Texas Southwestern Medical Center6, Francis Crick Institute7, Bayer8, New York University9, Université catholique de Louvain10, Vrije Universiteit Brussel11, Tokyo University of Marine Science and Technology12
TL;DR: In several human and mouse cancer cell lines and carcinomas, a sapienate biosynthesis pathway underpins metabolic plasticity by allowing these cells to bypass stearoyl-CoA desaturase-dependent fatty acid desaturation.
Abstract: Most tumours have an aberrantly activated lipid metabolism1,2 that enables them to synthesize, elongate and desaturate fatty acids to support proliferation. However, only particular subsets of cancer cells are sensitive to approaches that target fatty acid metabolism and, in particular, fatty acid desaturation3. This suggests that many cancer cells contain an unexplored plasticity in their fatty acid metabolism. Here we show that some cancer cells can exploit an alternative fatty acid desaturation pathway. We identify various cancer cell lines, mouse hepatocellular carcinomas, and primary human liver and lung carcinomas that desaturate palmitate to the unusual fatty acid sapienate to support membrane biosynthesis during proliferation. Accordingly, we found that sapienate biosynthesis enables cancer cells to bypass the known fatty acid desaturation pathway that is dependent on stearoyl-CoA desaturase. Thus, only by targeting both desaturation pathways is the in vitro and in vivo proliferation of cancer cells that synthesize sapienate impaired. Our discovery explains metabolic plasticity in fatty acid desaturation and constitutes an unexplored metabolic rewiring in cancers. In several human and mouse cancer cell lines and carcinomas, a sapienate biosynthesis pathway underpins metabolic plasticity by allowing these cells to bypass stearoyl-CoA desaturase-dependent fatty acid desaturation.
283 citations
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TL;DR: The Tohoku region, Northeast Japan, was hit by a gigantic earthquake in 2011, and subsequently by a giant tsunami as discussed by the authors, which caused huge damage on the eastern coast Japan.
Abstract: The Tohoku region, Northeast Japan, was hit by a gigantic earthquake which occurred in the Pacific close to Tohoku, and subsequently by a giant tsunami. These hazards have caused huge damage on the eastern coast Japan. The earthquake’s magnitude was 9.0, the strongest ever recorded in Japan. The tsunami was also historical as its run-up height reached over 39 m. As of early May, 2011, over 24 thousand people were reported as dead or missing. Moreover, serious accidents at the Fukushima Nuclear Power Plants No.1 were caused by the effects of the tsunami. Therefore, the damage faced by Japanese people can be seen as a giant composite disaster. Although Japan, and the northeast of Japan in particular, has over a long time period increased its preparedness against earthquakes and tsunamis, huge damage still occurred. This paper considers why this tragedy occurred, and what unrecognized factors contributed to the high vulnerability of the area. To assist in answering such questions, this paper presents a timely report of the features of the earthquake and tsunami, the damage they caused, and the early efforts for recovery and reconstruction.
280 citations
Authors
Showing all 720 results
Name | H-index | Papers | Citations |
---|---|---|---|
Makoto Matsuoka | 94 | 382 | 32679 |
Murat Dogru | 62 | 315 | 15992 |
Shinichi Kikuchi | 58 | 281 | 9520 |
Michio Kondo | 57 | 424 | 11033 |
Kazuharu Bamba | 54 | 247 | 12228 |
Shinichi Konno | 45 | 293 | 6284 |
Michio Aoyama | 44 | 190 | 5952 |
Shiro Shigeta | 44 | 243 | 6316 |
Masaaki Nakayama | 40 | 236 | 7811 |
Hideki Ishii | 39 | 357 | 5808 |
Sheng Xu | 35 | 128 | 3453 |
Kazuhito Ichii | 34 | 96 | 5060 |
Yukihiko Kawasaki | 31 | 180 | 2816 |
Hiroyuki Yaginuma | 28 | 79 | 2726 |
Takeyoshi Yoshida | 28 | 104 | 2440 |