Label-Free Biosensing With a Slot-Waveguide-Based Ring Resonator in Silicon on Insulator

TLDR: In this article, a slot waveguide-based ring resonator with a footprint of only 13 mum times 10 mum, fabricated with optical lithography, was presented for selective label-free sensing of proteins.

Abstract: We present a slot-waveguide-based ring resonator in silicon on insulator (SOI) with a footprint of only 13 mum times 10 mum, fabricated with optical lithography. Experiments show that it has 298 nm/RIU sensitivity and a detection limit of 4.2middot10-5 RIU for changes in the refractive index of the top cladding. We prove for the first time that surface chemistry for selective label-free sensing of proteins can be applied inside a 100 nm-wide slot region and demonstrate that the application of a slot waveguide instead of a normal waveguide increases the sensitivity of an SOI ring resonator with a factor 3.5 for the detection of proteins.