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Alexandra M. Allen
Researcher at University of Bristol
Publications - 28
Citations - 4664
Alexandra M. Allen is an academic researcher from University of Bristol. The author has contributed to research in topics: SNP genotyping & Genetic diversity. The author has an hindex of 18, co-authored 28 publications receiving 3918 citations.
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Journal ArticleDOI
Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array
Shichen Wang,Debbie Wong,Kerrie Forrest,Alexandra M. Allen,Shiaoman Chao,Bevan Emma Huang,Marco Maccaferri,Silvio Salvi,Sara Giulia Milner,Luigi Cattivelli,Anna M. Mastrangelo,Alex Whan,Stuart Stephen,Gary L A Barker,Ralf Wieseke,Joerg Plieske,Morten Lillemo,Diane E. Mather,Rudi Appels,Rudy Dolferus,Gina Brown-Guedira,Abraham B. Korol,Alina Akhunova,Catherine Feuillet,Catherine Feuillet,Jérôme Salse,Michele Morgante,Curtis J. Pozniak,Ming-Cheng Luo,Jan Dvorak,Matthew K. Morell,Jorge Dubcovsky,Jorge Dubcovsky,Martin W. Ganal,Roberto Tuberosa,Cindy Lawley,Ivan Mikoulitch,Colin Cavanagh,Keith J. Edwards,Matthew J. Hayden,Eduard Akhunov +40 more
TL;DR: The developed array and cluster identification algorithms provide an opportunity to infer detailed haplotype structure in polyploid wheat and will serve as an invaluable resource for diversity studies and investigating the genetic basis of trait variation in wheat.
Journal ArticleDOI
Analysis of the bread wheat genome using whole-genome shotgun sequencing
Rachel Brenchley,Manuel Spannagl,Matthias Pfeifer,Gary L A Barker,Rosalinda D’Amore,Alexandra M. Allen,Neil McKenzie,Melissa Kramer,Arnaud Kerhornou,Dan Bolser,Suzanne Kay,Darren Waite,Martin Trick,Ian Bancroft,Y. Q. Gu,Naxin Huo,Ming-Cheng Luo,Sunish K. Sehgal,Bikram S. Gill,S. F. Kianian,Olin D. Anderson,Paul J. Kersey,Jan Dvorak,W. Richard McCombie,Anthony Hall,Klaus F. X. Mayer,Keith J. Edwards,Michael W. Bevan,Neil Hall +28 more
TL;DR: It is shown that the hexaploid genome is highly dynamic, with significant loss of gene family members on polyploidization and domestication, and an abundance of gene fragments.
Journal ArticleDOI
High-density SNP genotyping array for hexaploid wheat and its secondary and tertiary gene pool
Mark O. Winfield,Alexandra M. Allen,Amanda J. Burridge,Gary L A Barker,Harriet R. Benbow,Paul A. Wilkinson,Jane A. Coghill,Christy Waterfall,Alessandro Davassi,Geoff Scopes,Ali Pirani,Teresa Webster,Fiona Brew,Claire Bloor,Julie King,Claire West,Simon Griffiths,Ian P. King,Alison R. Bentley,Keith J. Edwards +19 more
TL;DR: The identification of a large number of single nucleotide polymorphisms that can be used to genotype hexaploid wheat and to identify and track introgressions from a variety of sources are described.
Journal ArticleDOI
Transcript-specific, single-nucleotide polymorphism discovery and linkage analysis in hexaploid bread wheat Triticum aestivum L
Alexandra M. Allen,Gary L A Barker,Simon Berry,Jane A. Coghill,Rhian Gwilliam,Susan Kirby,Phil Robinson,Rachel Brenchley,Rosalinda D’Amore,Neil McKenzie,Darren Waite,Anthony Hall,Michael W. Bevan,Neil Hall,Keith J. Edwards +14 more
TL;DR: To mine selected elite wheat germplasm for intervarietal single-nucleotide polymorphisms, expressed sequence tags derived from public sequencing programmes and next-generation sequencing of normalized wheat complementary DNA libraries are used, in combination with a novel sequence alignment and assembly approach.
Journal ArticleDOI
Characterization of a Wheat Breeders' Array suitable for high-throughput SNP genotyping of global accessions of hexaploid bread wheat (Triticum aestivum).
Alexandra M. Allen,Mark O. Winfield,Amanda J. Burridge,Rowena C Downie,Harriet L Benbow,Gary L A Barker,Paul A. Wilkinson,Jane A. Coghill,Christy Waterfall,Alessandro Davassi,Geoff Scopes,Ali Pirani,Teresa Webster,Fiona Brew,Claire Bloor,Simon Griffiths,Alison R. Bentley,Mark Alda,Peter Jack,Andrew L. Phillips,Keith J. Edwards +20 more
TL;DR: The identification of 35 143 single nucleotide polymorphism‐based markers are described, which are highly suited to the genotyping of elite hexaploid wheat accessions and are suitable for generating high‐density genetic maps of previously uncharacterized populations and for characterizing novel genetic diversity produced by mutagenesis.