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Keith J. Edwards
Researcher at University of Bristol
Publications - 175
Citations - 20901
Keith J. Edwards is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Gene. The author has an hindex of 63, co-authored 168 publications receiving 19087 citations. Previous affiliations of Keith J. Edwards include University of Sheffield & University of Hertfordshire.
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Journal ArticleDOI
A high-density microsatellite consensus map for bread wheat (Triticum aestivum L.)
TL;DR: This consensus map represents the highest-density public microsatellite map of wheat and is accompanied by an allele database showing the parent allele sizes for every marker mapped, which enables users to predict allele sizes in new breeding populations and develop molecular breeding and genomics strategies.
Journal ArticleDOI
Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array
Shichen Wang,Debbie Wong,Kerrie Forrest,Alexandra M. Allen,Shiaoman Chao,Bevan Emma Huang,Marco Maccaferri,Silvio Salvi,Sara Giulia Milner,Luigi Cattivelli,Anna M. Mastrangelo,Alex Whan,Stuart Stephen,Gary L A Barker,Ralf Wieseke,Joerg Plieske,Morten Lillemo,Diane E. Mather,Rudi Appels,Rudy Dolferus,Gina Brown-Guedira,Abraham B. Korol,Alina Akhunova,Catherine Feuillet,Catherine Feuillet,Jérôme Salse,Michele Morgante,Curtis J. Pozniak,Ming-Cheng Luo,Jan Dvorak,Matthew K. Morell,Jorge Dubcovsky,Jorge Dubcovsky,Martin W. Ganal,Roberto Tuberosa,Cindy Lawley,Ivan Mikoulitch,Colin Cavanagh,Keith J. Edwards,Matthew J. Hayden,Eduard Akhunov +40 more
TL;DR: The developed array and cluster identification algorithms provide an opportunity to infer detailed haplotype structure in polyploid wheat and will serve as an invaluable resource for diversity studies and investigating the genetic basis of trait variation in wheat.
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Nested Retrotransposons in the Intergenic Regions of the Maize Genome
Phillip SanMiguel,Alexander Tikhonov,Young Kwan Jin,Natasha Motchoulskaia,Dmitrii Zakharov,Admasu Melake-Berhan,Patricia S. Springer,Keith J. Edwards,Michael Lee,Zoya V Avramova,Jeffrey L. Bennetzen +10 more
TL;DR: Diagnostic sequencing indicated that a 280-kilobase region containing the maize Adh1-F and u22 genes is composed primarily of retrotransposons inserted within each other, and ten retroelement families were discovered.
Journal ArticleDOI
Predicting the functional, molecular, and phenotypic consequences of amino acid substitutions using hidden Markov models.
Hashem A. Shihab,Julian Gough,David Neil Cooper,Peter D. Stenson,Gary L A Barker,Keith J. Edwards,Ian N. M. Day,Tom R. Gaunt +7 more
TL;DR: The Functional Analysis Through Hidden Markov Models (FATHMM) software and server is described: a species‐independent method with optional species‐specific weightings for the prediction of the functional effects of protein missense variants, demonstrating that FATHMM can be efficiently applied to high‐throughput/large‐scale human and nonhuman genome sequencing projects with the added benefit of phenotypic outcome associations.
Journal ArticleDOI
Analysis of the bread wheat genome using whole-genome shotgun sequencing
Rachel Brenchley,Manuel Spannagl,Matthias Pfeifer,Gary L A Barker,Rosalinda D’Amore,Alexandra M. Allen,Neil McKenzie,Melissa Kramer,Arnaud Kerhornou,Dan Bolser,Suzanne Kay,Darren Waite,Martin Trick,Ian Bancroft,Y. Q. Gu,Naxin Huo,Ming-Cheng Luo,Sunish K. Sehgal,Bikram S. Gill,S. F. Kianian,Olin D. Anderson,Paul J. Kersey,Jan Dvorak,W. Richard McCombie,Anthony Hall,Klaus F. X. Mayer,Keith J. Edwards,Michael W. Bevan,Neil Hall +28 more
TL;DR: It is shown that the hexaploid genome is highly dynamic, with significant loss of gene family members on polyploidization and domestication, and an abundance of gene fragments.