B
Bengt Långström
Researcher at Uppsala University
Publications - 705
Citations - 32024
Bengt Långström is an academic researcher from Uppsala University. The author has contributed to research in topics: Positron emission tomography & Methyl iodide. The author has an hindex of 83, co-authored 700 publications receiving 30513 citations. Previous affiliations of Bengt Långström include Uppsala University Hospital & University of Southern Denmark.
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Journal ArticleDOI
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B.
William E. Klunk,Henry Engler,Agneta Nordberg,Yanming Wang,G. Blomqvist,Daniel P. Holt,Mats Bergström,Irina Savitcheva,Guo Feng Huang,Sergio Estrada,Birgitta Ausén,Manik L. Debnath,Julien Barletta,Julie C. Price,Johan Sandell,Brian J. Lopresti,Anders Wall,Pernilla Koivisto,Gunnar Antoni,Chester A. Mathis,Bengt Långström +20 more
TL;DR: The results suggest that PET imaging with the novel tracer, PIB, can provide quantitative information on amyloid deposits in living subjects.
Journal ArticleDOI
Imaging dopamine receptors in the human brain by positron tomography
Henry N. Wagner,H. Donald Burns,Robert F. Dannals,Dean F. Wong,Bengt Långström,Timothy Duelfer,J. James Frost,Hayden T. Ravert,Jonathan M. Links,Shelley B. Rosenbloom,Scott E. Lukas,Alfred V. Kramer,Michael J. Kuhar +12 more
TL;DR: The ligand 3-N-[11C]methylspiperone, which preferentially binds to dopamine receptors in vivo, was used to image the receptors by positron emission tomography scanning in baboons and in humans, and holds promise for noninvasive clinical studies of dopamine receptor in humans.
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Two-year follow-up of amyloid deposition in patients with Alzheimer's disease.
Henry Engler,Anton Forsberg,Ove Almkvist,Gunnar Blomquist,Emma Larsson,Irina Savitcheva,Anders Wall,Anna Ringheim,Bengt Långström,Agneta Nordberg +9 more
TL;DR: Relatively stable PIB retention after 2 years of follow-up in patients with mild Alzheimer's disease suggests that amyloid deposition in the brain reaches a plateau by the early clinical stages of Alzheimer’s disease and therefore may precede a decline in rCMRGlc and cognition.
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Common Changes in Cerebral Blood Flow in Patients With Social Phobia Treated With Citalopram or Cognitive-Behavioral Therapy
Tomas Furmark,Maria Tillfors,Ina Marteinsdottir,Håkan Fischer,Anna Pissiota,Bengt Långström,Mats Fredrikson +6 more
TL;DR: Improvement in symptoms with citalopram and cognitive-behavioral therapy was accompanied by a decreased rCBF-response to public speaking bilaterally in the amygdala, hippocampus, and the periamygdaloid, rhinal, and parahippocampal cortices, confirmed by between-group comparisons.
Journal ArticleDOI
Mapping human brain monoamine oxidase A and B with 11C-labeled suicide inactivators and PET.
Joanna S. Fowler,Robert R. MacGregor,Alfred P. Wolf,Carroll D. Arnett,Stephen L. Dewey,David J. Schlyer,David R. Christman,Jean Logan,Maynard E. Smith,H. Sachs,Sten-Magnus Aquilonius,Peter Bjurling,Christer Halldin,Per Hartvig,Klaus L. Leenders,Hans Lundqvist,Lars Oreland,C.-G. Stålnacke,Bengt Långström +18 more
TL;DR: Suicide enzyme inactivators labeled with positron emitters can be used to quantitate the distribution and kinetic characteristics of MAO in human brain structures and show rapid clearance of the inactive enantiomer and retention of the active enantiomers within MAO B-rich brain structures.