Journal ArticleDOI
An Overview of Regular Dialysis Treatment in Japan (As of 31 December 2013)
Ikuto Masakane,Shigeru Nakai,Satoshi Ogata,Naoki Kimata,Norio Hanafusa,Takayuki Hamano,Kenji Wakai,Atsushi Wada,Kosaku Nitta +8 more
TLDR
The number of patients who underwent hemodiafiltration (HDF) at the end of 2013 was 31 371, a marked increase from that in 2012, and the number of Patients who underwent online HDF increased approximately fivefold over the last 2 years.Abstract:
A nationwide survey of 4325 dialysis facilities was conducted at the end of 2013, among which 4268 (98.7%) responded. The number of new dialysis patients was 38,095 in 2013. Since 2008, the number of new dialysis patients has remained almost the same without any marked increase or decrease. The number of dialysis patients who died in 2013 was 30,751. The dialysis patient population has been growing every year in Japan; it was 314,438 at the end of 2013. The number of dialysis patients per million at the end of 2013 was 2470. The crude death rate of dialysis patients in 2013 was 9.8%. The mean age of new dialysis patients was 68.7 years and the mean age of the entire dialysis patient population was 67.2 years. The most common primary cause of renal failure among new dialysis patients was diabetic nephropathy (43.8%). The actual number of new dialysis patients with diabetic nephropathy has almost been unchanged for the last few years. Diabetic nephropathy was also the most common primary disease among the entire dialysis patient population (37.6%), followed by chronic glomerulonephritis (32.4%). The percentage of dialysis patients with diabetic nephropathy has been increasing continuously, whereas the percentage of dialysis patients with chronic glomerulonephritis has been decreasing. The number of patients who underwent hemodiafiltration (HDF) at the end of 2013 was 31,371, a marked increase from that in 2012. This number is more than twice that at the end of 2011 and approximately 1.5 times the number at the end of 2012. In particular, the number of patients who underwent online HDF increased approximately fivefold over the last 2 years. Among 151,426 dialysis patients with primary causes of renal failure other than diabetic nephropathy, 10.8% had a history of diabetes. Among those with a history of diabetes, 26.8% used glycoalbumin as an indicator of blood glucose level; and 33.0 and 27.6% were administered insulin and dipeptidyl peptidase (DPP)-4 inhibitor, respectively, as a medication of diabetes. The facility survey showed that 9392 patients underwent peritoneal dialysis (PD). The patient survey revealed that 1920 of these PD patients also underwent another dialysis method using extracorporeal circulation, such as hemodialysis (HD) or HDF. The number of patients who underwent HD at home at the end of 2013 was 461, a marked increase from that at the end of 2012 (393).read more
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The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019)
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TL;DR: For most patients with ESKD worldwide who are treated with in-centre haemodialysis, overall survival is poor, but longer in some Asian countries than elsewhere in the world, and longer in Europe than in the USA, although this gap has reduced.
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Spironolactone reduces cardiovascular and cerebrovascular morbidity and mortality in hemodialysis patients.
Yoshihiro Matsumoto,Yasuo Mori,Shinji Kageyama,Kazuo Arihara,Toshikazu Sugiyama,Hiromichi Ohmura,Toru Yakushigawa,Hatsumi Sugiyama,Yasushi Shimada,Youichi Nojima,Nobuo Shio +10 more
TL;DR: Aldosterone receptor blockade using spironolactone may substantially reduce the risk of both CCV morbidity and death among HD patients; however, larger-scale studies are recommended to further confirm its efficacy.
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The heart and vascular system in dialysis
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Shigeru Nakai,Kazuyuki Suzuki,Ikuto Masakane,Atsushi Wada,Noritomo Itami,Satoshi Ogata,Naoki Kimata,Takashi Shigematsu,Toshio Shinoda,Tetsuo Syouji,Masatomo Taniguchi,Kenji Tsuchida,Hidetomo Nakamoto,Shinichi Nishi,Hiroshi Nishi,Seiji Hashimoto,Takeshi Hasegawa,Norio Hanafusa,Takayuki Hamano,Naohiko Fujii,Seiji Marubayashi,Osamu Morita,Kunihiro Yamagata,Kenji Wakai,Yuzo Watanabe,Kunitoshi Iseki,Yoshiharu Tsubakihara +26 more
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