Numerical index of the discriminatory ability of typing systems: an application of Simpson's index of diversity.
Paul R. Hunter,M A Gaston +1 more
TLDR
An index of discrimination for typing methods is described, based on the probability of two unrelated strains being characterized as the same type, which may be used to compare typing methods and select the most discriminatory system.Abstract:
An index of discrimination for typing methods is described, based on the probability of two unrelated strains being characterized as the same type. This index may be used to compare typing methods and select the most discriminatory system.read more
Citations
More filters
Journal ArticleDOI
Guidelines for the validation and application of typing methods for use in bacterial epidemiology
A. van Belkum,Panayotis T. Tassios,Lenie Dijkshoorn,Sara Hæggman,Barry Cookson,Norman K. Fry,V. Fussing,Jonathan Green,Edward J. Feil,Peter Gerner-Smidt,Sylvain Brisse,Marc Struelens +11 more
TL;DR: Newer and older, phenotypic and genotypic methods for typing of all clinically relevant bacterial species are described according to their principles, advantages and disadvantages and Criteria for their evaluation and application and the interpretation of their results are proposed.
Journal ArticleDOI
The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis
Maxine Caws,Maxine Caws,Guy E. Thwaites,Sarah J. Dunstan,Sarah J. Dunstan,Thomas R. Hawn,Nguyen Ngoc Lan,Nguyen Thuy Thuong Thuong,Kasia Stepniewska,Mai N. T. Huyen,Nguyen Duc Bang,Tran Huu Loc,Sebastien Gagneux,Dick van Soolingen,Kristin Kremer,Marianne A B van der Sande,Peter M. Small,Peter M. Small,Phan Thi Hoang Anh,Nguyen Tran Chinh,Hoang Thi Quy,Nguyen Thi Hong Duyen,Dau Quang Tho,Nguyen Trong Hieu,Estee Torok,Estee Torok,Tran Tinh Hien,Nguyen Huy Dung,Nguyen Thi Quynh Nhu,Phan Minh Duy,Nguyen Van Vinh Chau,Jeremy Farrar,Jeremy Farrar +32 more
TL;DR: Evidence that M. tuberculosis genotype influences clinical disease phenotype is provided and a significant interaction between host and bacterial genotypes and the development of tuberculosis is demonstrated for the first time.
Journal ArticleDOI
spa Typing Method for Discriminating among Staphylococcus aureus Isolates: Implications for Use of A Single Marker to Detect Genetic Micro- and Macrovariation
Larry Koreen,Srinivas V. Ramaswamy,Edward A. Graviss,Steven Naidich,James M. Musser,James M. Musser,Barry N. Kreiswirth +6 more
TL;DR: It is determined that S. aureus likely has a primarily clonal population structure and that spa typing can singly index genetic variation with 88% direct concordance with the microarray and can correctly assign isolates to phylogenetic lineages.
Journal ArticleDOI
Surrounded by mycobacteria: nontuberculous mycobacteria in the human environment.
TL;DR: The widespread distribution of the nontuberculous mycobacteria in the environment, coupled with their ability to degrade and metabolize a variety of complex hydrocarbons including pollutants, suggests that NTM may be agents of nutrient cycling.
Journal ArticleDOI
Determining Confidence Intervals When Measuring Genetic Diversity and the Discriminatory Abilities of Typing Methods for Microorganisms
TL;DR: A method for determining confidence intervals for a commonly used index of diversity facilitates the comparison of the genetic population structure of microorganisms isolated from different environments and improves the objective assessment of the discriminatory power of typing techniques.
References
More filters
Journal ArticleDOI
Measurement of diversity
TL;DR: In this article, the authors define and examine a measure of concentration in terms of population constants, and examine the relationship between the characteristic and the index of diversity when both are applied to a logarithmic distribution.
Journal ArticleDOI
Application of DNA typing methods to epidemiology and taxonomy of Candida species.
S Scherer,D A Stevens +1 more
TL;DR: DNA typing methods appear to offer important potential advantages over phenotyping methods, and provide a base for further epidemiologic studies and for further development of techniques, such as the use of cloned probes for studies of DNA homology.
Journal ArticleDOI
Killer system: a simple method for differentiating Candida albicans strains.
TL;DR: By using a simple system, it was possible to differentiate up to 512 isolates of C. albicans according to their susceptibility to the killer effect of nine selected killer yeasts, and the use of this method as an epidemiological marker in the case of presumptive nosocomial infections due to C.Albicans is reported.
Journal ArticleDOI
Fingerprinting Candida albicans.
TL;DR: A new method of typing Candida albicans based on immunoblotting is described, which was much more sensitive than the serotyping and morphotyping methods and lacked the phenotypic variability of the biotyping procedure previously used to define the outbreak.
Journal ArticleDOI
Preliminary investigation of Candida albicans biovars.
TL;DR: A total of 126 Candida albicans strains were enzymatically evaluated by the API ZYM system, and four enzymologically based groups of C. al bicans are recognized.
Related Papers (5)
Proposal for Standardization of Optimized Mycobacterial Interspersed Repetitive Unit-Variable-Number Tandem Repeat Typing of Mycobacterium tuberculosis
Philip Supply,Philip Supply,Caroline Allix,Sarah Lesjean,Sarah Lesjean,Mara Cardoso-Oelemann,Mara Cardoso-Oelemann,Sabine Rüsch-Gerdes,Eve Willery,Eve Willery,Evgueni Savine,Evgueni Savine,Petra E. W. de Haas,Henk van Deutekom,Solvig Roring,Pablo Bifani,Natalia Kurepina,Barry N. Kreiswirth,Christophe Sola,Nalin Rastogi,Vincent Vatin,Vincent Vatin,Maria Cristina Gutierrez,Maryse Fauville,Stefan Niemann,Robin A. Skuce,Kristin Kremer,Camille Locht,Camille Locht,Dick van Soolingen +29 more