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Danette Hartzell
Researcher at Promega
Publications - 5
Citations - 1891
Danette Hartzell is an academic researcher from Promega. The author has contributed to research in topics: Promoter & Binding site. The author has an hindex of 4, co-authored 5 publications receiving 1544 citations.
Papers
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Journal ArticleDOI
HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis
Georgyi V. Los,Lance P. Encell,Mark McDougall,Danette Hartzell,Natasha Karassina,Chad Zimprich,Monika G. Wood,Randy Learish,Rachel Friedman Ohana,Marjeta Urh,Daniel J. Simpson,Jacqui Méndez,Kris Zimmerman,Paul Otto,Gediminas Vidugiris,Ji Zhu,Aldis Darzins,Dieter Klaubert,Robert F. Bulleit,Keith V. Wood +19 more
TL;DR: The utility of this modular protein tagging system for cellular imaging and protein immobilization is demonstrated by analyzing multiple molecular processes associated with NF-kappaB-mediated cellular physiology, including imaging of subcellular protein translocation and capture of protein--protein and protein--DNA complexes.
Journal ArticleDOI
A functional analysis of the CREB signaling pathway using HaloCHIP-chip and high throughput reporter assays
Danette Hartzell,Nathan D. Trinklein,Jacqui Méndez,Nancy Murphy,Shelley Force Aldred,Keith V. Wood,Marjeta Urh +6 more
TL;DR: Analysis of CREB genome-wide binding events using a comprehensive DNA microarray of human promoters suggests for the first time that TORC1 provides directional information when CREB is bound at bidirectional promoters and possible pausing of the CREB protein after initial transcriptional activation.
Book ChapterDOI
Methods for Detection of Protein–Proteinnl and Protein–DNA Interactions Using HaloTag ™
TL;DR: A procedure for immobilization of HaloTag fusion proteins and how immobilized proteins can be used to study protein-protein and protein-DNA interactions in vivo and in vitro is described.
Patent
Compositions and methods for capturing and analyzing cross-linked biomolecules
TL;DR: In this paper, the authors present methods, compositions and kits to capture cross-linked protein complexes to a support matrix in a stable, covalent bridge of attachment, which is used for cross-link protein attachment.
Journal Article
Influenza A H1N1: A Rapid Approach to Cloning and Protein Expression
Keehwan Kwon,Getahun Tsegaye,Patrick Burr,Yu Do,J. Sosa,T. Edeto,M. Gonzalez,P. Tangirala,B. Bishop,Ravi Sanka,J. Gilbert,Marjeta Urh,J. Vidugiriene,Danette Hartzell,Robert D. Fleischmann,S. Peters,Jeremy Hasseman +16 more
TL;DR: A rapid cloning and protein expression process was implemented using two clinical isolates to enable efficient distribution of materials for further characterization of Swine-derived Influenza A H1N1 virus.