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Danxia Gu
Researcher at Zhejiang University
Publications - 23
Citations - 4799
Danxia Gu is an academic researcher from Zhejiang University. The author has contributed to research in topics: Klebsiella pneumoniae & Plasmid. The author has an hindex of 11, co-authored 20 publications receiving 3550 citations.
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Journal ArticleDOI
Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: A microbiological and molecular biological study
Yiyun Liu,Yang Wang,Timothy R. Walsh,Ling-Xian Yi,Rong Zhang,James Spencer,Yohei Doi,Guo-Bao Tian,Baolei Dong,Xianhui Huang,Lin-Feng Yu,Danxia Gu,Hongwei Ren,Xiaojie Chen,Luchao Lv,Dandan He,Hongwei Zhou,Zi-sen Liang,Jian-Hua Liu,Jianzhong Shen +19 more
TL;DR: The emergence of MCR-1 heralds the breach of the last group of antibiotics, polymyxins, by plasmid-mediated resistance, in Enterobacteriaceae and emphasise the urgent need for coordinated global action in the fight against pan-drug-resistant Gram-negative bacteria.
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A fatal outbreak of ST11 carbapenem-resistant hypervirulent Klebsiella pneumoniae in a Chinese hospital: a molecular epidemiological study
Danxia Gu,Ning Dong,Zhiwei Zheng,Di Lin,Man Huang,Lihua Wang,Edward Wai-Chi Chan,Lingbin Shu,Jiang Yu,Rong Zhang,Sheng Chen +10 more
TL;DR: Genomic analyses showed that the emergence of these ST11 carbapenem-resistant hypervirulent K pneumoniae strains was due to the acquisition of a roughly 170 kbp pLVPK-like virulence plasmid by classic ST11 carbohydrate-resistant, multidrug resistant, and highly transmissible strains.
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Emergence of carbapenem-resistant serotype K1 hypervirulent Klebsiella pneumoniae strains in China
TL;DR: Findings indicate that K1 hvKP is simultaneously hypervirulent, multidrug resistant, and transmissible.
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Enterococcal isolates carrying the novel oxazolidinone resistance gene optrA from hospitals in Zhejiang, Guangdong, and Henan, China, 2010–2014
Jiachang Cai,Yang Wang,Stefan Schwarz,H. Lv,Y. Li,K. Liao,S. Yu,K. Zhao,Danxia Gu,X. Wang,Rong Zhang,Jianzhong Shen +11 more
TL;DR: Routine surveillance of optrA-positive enterococci in hospitals should be conducted to monitor and counteract their further dissemination, and the data of this study may be used as a baseline from which to judge future decreases or increases in optr A-positiveEnterococci.
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Detection of Colistin Resistance Gene mcr-1 in Hypervirulent Klebsiella pneumoniae and Escherichia coli Isolates from an Infant with Diarrhea in China.
TL;DR: Polymyxins have been resurrected as a last-resort treatment option for the global increase in the prevalence of carbapenem-resistant Enterobacteriaceae and are well-suited for use in wound healing.