G
Guo-Bao Tian
Researcher at Sun Yat-sen University
Publications - 47
Citations - 5371
Guo-Bao Tian is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: MCR-1 & Colistin. The author has an hindex of 18, co-authored 38 publications receiving 3903 citations. Previous affiliations of Guo-Bao Tian include Minzu University of China & Chinese Ministry of Education.
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Journal ArticleDOI
Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: A microbiological and molecular biological study
Yiyun Liu,Yang Wang,Timothy R. Walsh,Ling-Xian Yi,Rong Zhang,James Spencer,Yohei Doi,Guo-Bao Tian,Baolei Dong,Xianhui Huang,Lin-Feng Yu,Danxia Gu,Hongwei Ren,Xiaojie Chen,Luchao Lv,Dandan He,Hongwei Zhou,Zi-sen Liang,Jian-Hua Liu,Jianzhong Shen +19 more
TL;DR: The emergence of MCR-1 heralds the breach of the last group of antibiotics, polymyxins, by plasmid-mediated resistance, in Enterobacteriaceae and emphasise the urgent need for coordinated global action in the fight against pan-drug-resistant Gram-negative bacteria.
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Colistin and its role in the Era of antibiotic resistance: an extended review(2000–2019)
Mohamed Abd El-Gawad El-Sayed Ahmed,Mohamed Abd El-Gawad El-Sayed Ahmed,Lan Lan Zhong,Cong Shen,Yongqiang Yang,Yohei Doi,Yohei Doi,Guo-Bao Tian +7 more
TL;DR: This review intends to discuss the progress over the last two decades in understanding the alternative colistin mechanisms of action and different strategies used by bacteria to develop resistance againstcolistin, besides providing an update about what is previously recognized and what is novel concerning colistsin resistance.
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Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study
Yang Wang,Guo-Bao Tian,Rong Zhang,Yingbo Shen,Jonathan M. Tyrrell,Xi Huang,Hongwei Zhou,Lei Lei,Hongyu Li,Yohei Doi,Ying Fang,Hongwei Ren,Lan-Lan Zhong,Zhangqi Shen,Kun-Jiao Zeng,Shaolin Wang,Jian-Hua Liu,Congming Wu,Timothy R. Walsh,Jianzhong Shen +19 more
TL;DR: The prevalence of MCRPE in human infections and carriage, clinical associations of mcr-1-positive Escherichia coli (M CRPEC) infection, and risk factors for MCRPEC carriage are reported.
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Dissemination and Mechanism for the MCR-1 Colistin Resistance
Rongsui Gao,Yongfei Hu,Zhencui Li,Jian Sun,Qingjing Wang,Jingxia Lin,Huiyan Ye,Fei Liu,Swaminath Srinivas,Defeng Li,Baoli Zhu,Ya-Hong Liu,Guo-Bao Tian,Youjun Feng +13 more
TL;DR: The comparative genomics of two new mCR-1-harbouring plasmids isolated from the human gut microbiota are reported, highlighting the diversity in plasmid transfer of the mcr-1 gene and provids a first glimpse of mechanism for the MCR- 1-mediated colistin resistance.
Journal ArticleDOI
Possible Transmission of mcr-1-Harboring Escherichia coli between Companion Animals and Human.
Xue Fei Zhang,Xue Fei Zhang,Yohei Doi,Xi Huang,Xi Huang,Hong Yu Li,Lan Lan Zhong,Lan Lan Zhong,Kun Jiao Zeng,Kun Jiao Zeng,Yan Fen Zhang,Yan Fen Zhang,Sandip Patil,Sandip Patil,Guo-Bao Tian,Guo-Bao Tian +15 more
TL;DR: In this paper, the authors reported detection of mcr-1 in colistin-resistant E coli isolated from companion animals and the possible transmission of mCR-1-harboring E coli between companion animals, and a person.