R
Rong Zhang
Researcher at Zhejiang University
Publications - 143
Citations - 10206
Rong Zhang is an academic researcher from Zhejiang University. The author has contributed to research in topics: Klebsiella pneumoniae & Plasmid. The author has an hindex of 35, co-authored 136 publications receiving 7172 citations. Previous affiliations of Rong Zhang include Osaka University.
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Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: A microbiological and molecular biological study
Yiyun Liu,Yang Wang,Timothy R. Walsh,Ling-Xian Yi,Rong Zhang,James Spencer,Yohei Doi,Guo-Bao Tian,Baolei Dong,Xianhui Huang,Lin-Feng Yu,Danxia Gu,Hongwei Ren,Xiaojie Chen,Luchao Lv,Dandan He,Hongwei Zhou,Zi-sen Liang,Jian-Hua Liu,Jianzhong Shen +19 more
TL;DR: The emergence of MCR-1 heralds the breach of the last group of antibiotics, polymyxins, by plasmid-mediated resistance, in Enterobacteriaceae and emphasise the urgent need for coordinated global action in the fight against pan-drug-resistant Gram-negative bacteria.
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A fatal outbreak of ST11 carbapenem-resistant hypervirulent Klebsiella pneumoniae in a Chinese hospital: a molecular epidemiological study
Danxia Gu,Ning Dong,Zhiwei Zheng,Di Lin,Man Huang,Lihua Wang,Edward Wai-Chi Chan,Lingbin Shu,Jiang Yu,Rong Zhang,Sheng Chen +10 more
TL;DR: Genomic analyses showed that the emergence of these ST11 carbapenem-resistant hypervirulent K pneumoniae strains was due to the acquisition of a roughly 170 kbp pLVPK-like virulence plasmid by classic ST11 carbohydrate-resistant, multidrug resistant, and highly transmissible strains.
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Novel Plasmid-Mediated Colistin Resistance Gene mcr-3 in Escherichia coli.
Wenjuan Yin,Hui Li,Yingbo Shen,Zhihai Liu,Shaolin Wang,Zhangqi Shen,Rong Zhang,Timothy R. Walsh,Jianzhong Shen,Yang Wang +9 more
TL;DR: The results suggest the likelihood of a wide dissemination of the novel mobile colistin resistance gene mCR-3 among Enterobacteriaceae and aeromonads; the latter may act as a potential reservoir for mcr-3.
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A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal origin
Yang Wang,Yuan Lv,Jiachang Cai,Stefan Schwarz,Lanqing Cui,Zhidong Hu,Rong Zhang,Jun Li,Qin Zhao,Tao He,Dacheng Wang,Zheng Wang,Yingbo Shen,Yun Li,Andrea T. Feßler,Congming Wu,Hao Yu,Xuming Deng,Xi Xia,Jianzhong Shen +19 more
TL;DR: The identification of a novel oxazolidinone resistance gene, optrA, and a first investigation of the extent to which this gene was present in E. faecalis and Enterococcus faecium are reported.
Journal ArticleDOI
Emergence of plasmid-mediated high-level tigecycline resistance genes in animals and humans
Tao He,Ran Wang,Dejun Liu,Timothy R. Walsh,Timothy R. Walsh,Rong Zhang,Yuan Lv,Yuebin Ke,Quanjiang Ji,Ruicheng Wei,Zhihai Liu,Yingbo Shen,Gang Wang,Lichang Sun,Lei Lei,Ziquan Lv,Yun Li,Maoda Pang,L Wang,Qiaoling Sun,Yulin Fu,Huangwei Song,Yuxin Hao,Zhangqi Shen,Shaolin Wang,Gong-Xiang Chen,Congming Wu,Jianzhong Shen,Yang Wang +28 more
TL;DR: The findings suggest that both the surveillance of tet(X) variants in clinical and animal sectors and the use of tetracyclines in food production require urgent global attention.