J
Jack W. Kent
Researcher at Texas Biomedical Research Institute
Publications - 96
Citations - 5579
Jack W. Kent is an academic researcher from Texas Biomedical Research Institute. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 33, co-authored 94 publications receiving 4919 citations. Previous affiliations of Jack W. Kent include University of Texas Health Science Center at San Antonio.
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Journal ArticleDOI
Common genetic variants influence human subcortical brain structures.
Derrek P. Hibar,Jason L. Stein,Jason L. Stein,Miguel E. Rentería,Alejandro Arias-Vasquez,Sylvane Desrivières,Neda Jahanshad,Roberto Toro,Roberto Toro,Katharina Wittfeld,Katharina Wittfeld,Lucija Abramovic,Micael Andersson,Benjamin S. Aribisala,Benjamin S. Aribisala,Nicola J. Armstrong,Nicola J. Armstrong,Manon Bernard,Marc M. Bohlken,Marco P. Boks,Janita Bralten,Andrew A. Brown,M. Mallar Chakravarty,M. Mallar Chakravarty,Qiang Chen,Christopher R.K. Ching,Christopher R.K. Ching,Gabriel Cuellar-Partida,Anouk den Braber,Sudheer Giddaluru,Aaron Goldman,Oliver Grimm,Tulio Guadalupe,Johanna Hass,Girma Woldehawariat,Avram J. Holmes,Avram J. Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil Lee,Phil Lee,Loes M. Olde Loohuis,Michelle Luciano,Christine Macare,Karen A. Mather,Manuel Mattheisen,Manuel Mattheisen,Yuri Milaneschi,Kwangsik Nho,Martina Papmeyer,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Shannon L. Risacher,Roberto Roiz-Santiañez,Emma J. Rose,Alireza Salami,Alireza Salami,Philipp G. Sämann,Lianne Schmaal,Andrew J. Schork,Jean Shin,Lachlan T. Strike,Lachlan T. Strike,Alexander Teumer,Marjolein M.J. van Donkelaar,Kristel R. van Eijk,Raymond K. Walters,Raymond K. Walters,Lars T. Westlye,Christopher D. Whelan,Anderson M. Winkler,Anderson M. Winkler,Marcel P. Zwiers,Saud Alhusaini,Saud Alhusaini,Lavinia Athanasiu,Stefan Ehrlich,Stefan Ehrlich,Marina Hakobjan,Cecilie B. Hartberg,Unn K. Haukvik,Angelien Heister,D. Hoehn,Dalia Kasperaviciute,Dalia Kasperaviciute,David C. Liewald,Lorna M. Lopez,Remco R. R. Makkinje,Mar Matarin,Marlies Naber,D. Reese McKay,Margaret Needham,Allison C. Nugent,Benno Pütz,Natalie A. Royle,Li Shen,Emma Sprooten,Emma Sprooten,Daniah Trabzuni,Daniah Trabzuni,Saskia S. L. van der Marel,Kimm J. E. van Hulzen,Esther Walton,Christiane Wolf,Laura Almasy,Laura Almasy,David Ames,David Ames,Sampath Arepalli,Amelia A. Assareh,Mark E. Bastin,Henry Brodaty,Kazima B. Bulayeva,Melanie A. Carless,Sven Cichon,Sven Cichon,Aiden Corvin,Joanne E. Curran,Michael Czisch,Greig I. de Zubicaray,Allissa Dillman,Ravi Duggirala,Thomas D. Dyer,Thomas D. Dyer,Susanne Erk,Iryna O. Fedko,Luigi Ferrucci,Tatiana Foroud,Peter T. Fox,Peter T. Fox,Masaki Fukunaga,J. Raphael Gibbs,J. Raphael Gibbs,Harald H H Göring,Robert C. Green,Sebastian Guelfi,Narelle K. Hansell,Catharina A. Hartman,Katrin Hegenscheid,Andreas Heinz,Dena G. Hernandez,Dena G. Hernandez,Dirk J. Heslenfeld,Pieter J. Hoekstra,Florian Holsboer,Georg Homuth,Jouke-Jan Hottenga,Masashi Ikeda,Clifford R. Jack,Mark Jenkinson,Robert Johnson,Ryota Kanai,Ryota Kanai,Maria Keil,Jack W. Kent,Peter Kochunov,John B.J. Kwok,John B.J. Kwok,Stephen M. Lawrie,Xinmin Liu,Xinmin Liu,Dan L. Longo,Katie L. McMahon,Eva M. Meisenzahl,Ingrid Melle,Sebastian Mohnke,Grant W. Montgomery,Jeanette C. Mostert,Thomas W. Mühleisen,Mike A. Nalls,Thomas E. Nichols,Thomas E. Nichols,Lars Nilsson,Markus M. Nöthen,Kazutaka Ohi,Rene L. Olvera,Rocío Pérez-Iglesias,G. Bruce Pike,Steven G. Potkin,Ivar Reinvang,Simone Reppermund,Marcella Rietschel,Nina Romanczuk-Seiferth,Glenn D. Rosen,Dan Rujescu,Knut Schnell,Peter R. Schofield,Peter R. Schofield,Colin Smith,Vidar M. Steen,Jessika E. Sussmann,Anbupalam Thalamuthu,Arthur W. Toga,Bryan J. Traynor,Juan C. Troncoso,Jessica A. Turner,Maria C. Valdés Hernández,Dennis van 't Ent,Marcel P. van der Brug,Nic J.A. van der Wee,Marie-José van Tol,Dick J. Veltman,Thomas H. Wassink,Eric Westman,Ronald H. Zielke,Alan B. Zonderman,David G. Ashbrook,Reinmar Hager,Lu Lu,Lu Lu,Francis J. McMahon,Derek W. Morris,Derek W. Morris,Robert W. Williams,Han G. Brunner,Han G. Brunner,Randy L. Buckner,Jan K. Buitelaar,Wiepke Cahn,Vince D. Calhoun,Vince D. Calhoun,Gianpiero L. Cavalleri,Benedicto Crespo-Facorro,Anders M. Dale,Gareth E. Davies,Norman Delanty,Norman Delanty,Chantal Depondt,Srdjan Djurovic,Wayne C. Drevets,Wayne C. Drevets,Thomas Espeseth,Randy L. Gollub,Beng-Choon Ho,Wolfgang Hoffmann,Wolfgang Hoffmann,Norbert Hosten,René S. Kahn,Stephanie Le Hellard,Andreas Meyer-Lindenberg,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Matthias Nauck,Lars Nyberg,Massimo Pandolfo,Brenda W.J.H. Penninx,Joshua L. Roffman,Sanjay M. Sisodiya,Jordan W. Smoller,Jordan W. Smoller,Hans van Bokhoven,Neeltje E.M. van Haren,Henry Völzke,Henrik Walter,Michael W. Weiner,Wei Wen,Tonya White,Ingrid Agartz,Ingrid Agartz,Ole A. Andreassen,John Blangero,John Blangero,Dorret I. Boomsma,Rachel M. Brouwer,Dara M. Cannon,Dara M. Cannon,Mark R. Cookson,Eco J. C. de Geus,Ian J. Deary,Gary Donohoe,Gary Donohoe,Guillén Fernández,Simon E. Fisher,Simon E. Fisher,Clyde Francks,Clyde Francks,David C. Glahn,Hans J. Grabe,Oliver Gruber,Oliver Gruber,John Hardy,Ryota Hashimoto,Hilleke E. Hulshoff Pol,Erik G. Jönsson,Erik G. Jönsson,Iwona Kłoszewska,Simon Lovestone,Simon Lovestone,Venkata S. Mattay,Patrizia Mecocci,Colm McDonald,Andrew M. McIntosh,Roel A. Ophoff,Roel A. Ophoff,Tomáš Paus,Zdenka Pausova,Mina Ryten,Mina Ryten,Perminder S. Sachdev,Andrew J. Saykin,Andrew J. Saykin,Andrew Simmons,Andrew B. Singleton,Hilkka Soininen,Joanna M. Wardlaw,Michael E. Weale,Daniel R. Weinberger,Hieab H.H. Adams,Lenore J. Launer,Stephan Seiler,Reinhold Schmidt,Ganesh Chauhan,Claudia L. Satizabal,Claudia L. Satizabal,James T. Becker,Lisa R. Yanek,Sven J. van der Lee,Maritza Ebling,Bruce Fischl,Bruce Fischl,W. T. Longstreth,Douglas N. Greve,Helena Schmidt,Paul A. Nyquist,Louis N. Vinke,Cornelia M. van Duijn,Luting Xue,Bernard Mazoyer,Joshua C. Bis,Vilmundur Gudnason,Sudha Seshadri,Sudha Seshadri,M. Arfan Ikram,Nicholas G. Martin,Margaret J. Wright,Margaret J. Wright,Gunter Schumann,Barbara Franke,Barbara Franke,Paul M. Thompson,Sarah E. Medland +344 more
TL;DR: In this paper, the authors conduct genome-wide association studies of the volumes of seven subcortical regions and the intracranial volume derived from magnetic resonance images of 30,717 individuals from 50 cohorts.
Journal ArticleDOI
Identification of common variants associated with human hippocampal and intracranial volumes
Jason L. Stein,Sarah E. Medland,Sarah E. Medland,Alejandro Arias Vasquez,Alejandro Arias Vasquez,Derrek P. Hibar,Rudy E Senstad,Anderson M. Winkler,Anderson M. Winkler,Roberto Toro,Roberto Toro,Katja Appel,Katja Appel,Richard Barteček,Ørjan Bergmann,Manon Bernard,Andrew A. Brown,Dara M. Cannon,M. Mallar Chakravarty,Andrea Christoforou,Andrea Christoforou,Martin Domin,Oliver Grimm,Marisa O. Hollinshead,Marisa O. Hollinshead,Avram J. Holmes,Georg Homuth,Jouke-Jan Hottenga,Camilla Langan,Lorna M. Lopez,Narelle K. Hansell,Kristy S. Hwang,Sungeun Kim,Gonzalo Laje,Phil Lee,Xinmin Liu,Xinmin Liu,Eva Loth,Anbarasu Lourdusamy,Morten Mattingsdal,Sebastian Mohnke,Susana Muñoz Maniega,Kwangsik Nho,Kwangsik Nho,Allison C. Nugent,Carol O'Brien,Martina Papmeyer,Benno Pütz,Adaikalavan Ramasamy,Jerod M. Rasmussen,Mark Rijpkema,Mark Rijpkema,Shannon L. Risacher,J. Cooper Roddey,Emma J. Rose,Mina Ryten,Li Shen,Emma Sprooten,Eric Strengman,Alexander Teumer,Daniah Trabzuni,Jessica A. Turner,Kristel R. van Eijk,Theo G.M. van Erp,Marie-José van Tol,Marie-José van Tol,Marie-José van Tol,Katharina Wittfeld,Christiane Wolf,Saskia Woudstra,André Aleman,Saud Alhusaini,Laura Almasy,Elisabeth B. Binder,David G. Brohawn,Rita M. Cantor,Melanie A. Carless,Aiden Corvin,Michael Czisch,Joanne E. Curran,Gail Davies,Marcio Almeida,Norman Delanty,Norman Delanty,Chantal Depondt,Ravi Duggirala,Thomas D. Dyer,Susanne Erk,Jesen Fagerness,Peter T. Fox,Nelson B. Freimer,Michael Gill,Harald H H Göring,Donald J. Hagler,D. Hoehn,Florian Holsboer,Martine Hoogman,Norbert Hosten,Neda Jahanshad,Matthew P. Johnson,Dalia Kasperaviciute,Jack W. Kent,Peter Kochunov,Peter Kochunov,Jack L. Lancaster,Stephen M. Lawrie,David C. Liewald,René C.W. Mandl,Mar Matarin,Manuel Mattheisen,Eva M. Meisenzahl,Ingrid Melle,Ingrid Melle,Eric K. Moses,Thomas W. Mühleisen,Matthias Nauck,Markus M. Nöthen,Rene L. Olvera,Massimo Pandolfo,G. Bruce Pike,Ralf Puls,Ivar Reinvang,Miguel E. Rentería,Miguel E. Rentería,Marcella Rietschel,Joshua L. Roffman,Natalie A. Royle,Dan Rujescu,Jonathan Savitz,Jonathan Savitz,Hugo G. Schnack,Knut Schnell,Nina Y. Seiferth,Colin Smith,Vidar M. Steen,Vidar M. Steen,Maria del C. Valdés Hernández,Martijn P. van den Heuvel,Nic J.A. van der Wee,Nic J.A. van der Wee,Neeltje E.M. van Haren,Joris A. Veltman,Henry Völzke,Robert Walker,Lars T. Westlye,Christopher D. Whelan,Ingrid Agartz,Dorret I. Boomsma,Gianpiero L. Cavalleri,Anders M. Dale,Anders M. Dale,Srdjan Djurovic,Srdjan Djurovic,Wayne C. Drevets,Wayne C. Drevets,Peter Hagoort,Peter Hagoort,Peter Hagoort,Jeremy Hall,Andreas Heinz,Clifford R. Jack,Tatiana Foroud,Stephanie Le Hellard,Stephanie Le Hellard,Fabio Macciardi,Grant W. Montgomery,Jean-Baptiste Poline,David J. Porteous,Sanjay M. Sisodiya,John M. Starr,Jessika E. Sussmann,Arthur W. Toga,Dick J. Veltman,Henrik Walter,Michael W. Weiner,Joshua C. Bis,M. Arfan Ikram,Albert V. Smith,Vilmundur Gudnason,Christophe Tzourio,Christophe Tzourio,Meike W. Vernooij,Lenore J. Launer,Charles DeCarli,Sudha Seshadri,Ole A. Andreassen,Ole A. Andreassen,Liana G. Apostolova,Mark E. Bastin,John Blangero,Han G. Brunner,Randy L. Buckner,Sven Cichon,Giovanni Coppola,Giovanni Coppola,Greig I. de Zubicaray,Ian J. Deary,Gary Donohoe,Eco J. C. de Geus,Thomas Espeseth,Thomas Espeseth,Guillén Fernández,Guillén Fernández,Guillén Fernández,David C. Glahn,David C. Glahn,Hans J. Grabe,Hans J. Grabe,John Hardy,Hilleke E. Hulshoff Pol,Mark Jenkinson,René S. Kahn,Colm McDonald,Andrew M. McIntosh,Francis J. McMahon,Katie L. McMahon,Andreas Meyer-Lindenberg,Derek W. Morris,Bertram Müller-Myhsok,Thomas E. Nichols,Thomas E. Nichols,Roel A. Ophoff,Roel A. Ophoff,Tomáš Paus,Zdenka Pausova,Brenda W.J.H. Penninx,Steven G. Potkin,Philipp G. Sämann,Andrew J. Saykin,Gunter Schumann,Jordan W. Smoller,Joanna M. Wardlaw,Michael E. Weale,Nicholas G. Martin,Barbara Franke,Barbara Franke,Margaret J. Wright,Paul M. Thompson +237 more
TL;DR: In this article, the authors report genome-wide association meta-analyses and replication for mean bilateral hippocampal, total brain and intracranial volumes from a large multinational consortium.
Journal ArticleDOI
The transcriptional landscape of age in human peripheral blood
Marjolein J. Peters,Roby Joehanes,Luke C. Pilling,Claudia Schurmann,Claudia Schurmann,Karen N. Conneely,Joseph E. Powell,Eva Reinmaa,George L. Sutphin,Alexandra Zhernakova,Katharina Schramm,Yana A. Wilson,Sayuko Kobes,Taru Tukiainen,Taru Tukiainen,Yolande F. M. Ramos,Harald H H Göring,Myriam Fornage,Yongmei Liu,Sina A. Gharib,Barbara E. Stranger,Philip L. De Jager,Abraham Aviv,Daniel Levy,Joanne M. Murabito,Peter J. Munson,Tianxiao Huan,Albert Hofman,André G. Uitterlinden,Fernando Rivadeneira,Jeroen van Rooij,Lisette Stolk,Linda Broer,Michael M. P. J. Verbiest,Mila Jhamai,Pascal P. Arp,Andres Metspalu,Liina Tserel,Lili Milani,Nilesh J. Samani,Nilesh J. Samani,Pärt Peterson,Silva Kasela,Veryan Codd,Veryan Codd,Annette Peters,Cavin K. Ward-Caviness,Christian Herder,Melanie Waldenberger,Michael Roden,Paula Singmann,Sonja Zeilinger,Thomas Illig,Georg Homuth,Hans J. Grabe,Henry Völzke,Leif Steil,Thomas Kocher,Anna Murray,David Melzer,Hanieh Yaghootkar,Stefania Bandinelli,Eric K. Moses,Jack W. Kent,Joanne E. Curran,Matthew P. Johnson,Sarah Williams-Blangero,Harm-Jan Westra,Harm-Jan Westra,Harm-Jan Westra,Allan F. McRae,Jennifer A. Smith,Sharon L.R. Kardia,Iiris Hovatta,Iiris Hovatta,Markus Perola,Markus Perola,Markus Perola,Samuli Ripatti,Samuli Ripatti,Samuli Ripatti,Veikko Salomaa,Anjali K. Henders,Nicholas G. Martin,Alicia K. Smith,Divya Mehta,Elisabeth B. Binder,K. Maria Nylocks,Elizabeth M. Kennedy,Torsten Klengel,Jingzhong Ding,Astrid Suchy-Dicey,Daniel A. Enquobahrie,Jennifer A. Brody,Jerome I. Rotter,Yii-Der Ida Chen,Jeanine J. Houwing-Duistermaat,Margreet Kloppenburg,P. Eline Slagboom,Quinta Helmer,Wouter den Hollander,Shannon Bean,Towfique Raj,Noman Bakhshi,Qiao-Ping Wang,Lisa J. Oyston,Bruce M. Psaty,Bruce M. Psaty,Russell P. Tracy,Grant W. Montgomery,Stephen T. Turner,John Blangero,Ingrid Meulenbelt,Kerry J. Ressler,Jian Yang,Lude Franke,Johannes Kettunen,Johannes Kettunen,Johannes Kettunen,Peter M. Visscher,G. Gregory Neely,Ron Korstanje,Robert L. Hanson,Holger Prokisch,Luigi Ferrucci,Tõnu Esko,Tõnu Esko,Tõnu Esko,Alexander Teumer,Joyce B. J. van Meurs,Andrew D. Johnson,Mike A. Nalls,Dena G. Hernandez,Dena G. Hernandez,Mark R. Cookson,Raphael Gibbs,Raphael Gibbs,John Hardy,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Alan B. Zonderman,Allissa Dillman,Allissa Dillman,Bryan J. Traynor,Colin Smith,Dan L. Longo,Daniah Trabzuni,Daniah Trabzuni,Juan C. Troncoso,Marcel P. van der Brug,Marcel P. van der Brug,Michael E. Weale,Richard O'Brien,Robert L. Johnson,Robert Walker,Ronald H. Zielke,Sampath Arepalli,Mina Ryten,Andrew B. Singleton +158 more
TL;DR: Differences between transcriptomic age and chronological age are associated with biological features linked to ageing, such as blood pressure, cholesterol levels, fasting glucose, and body mass index and the transcriptomic prediction model adds biological relevance and complements existing epigenetic prediction models.
Journal ArticleDOI
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Yingchang Lu,Felix R. Day,Stefan Gustafsson,Stefan Gustafsson,Martin L. Buchkovich,Jianbo Na,Veronique Bataille,Veronique Bataille,Diana L. Cousminer,Zari Dastani,Alexander W. Drong,Tõnu Esko,David M. Evans,Mario Falchi,Mario Falchi,Mary F. Feitosa,Teresa Ferreira,Åsa K. Hedman,Robin Haring,Robin Haring,Pirro G. Hysi,Mark M. Iles,Anne E. Justice,Stavroula Kanoni,Stavroula Kanoni,Vasiliki Lagou,Rui Li,Xin Li,Adam E. Locke,Chen Lu,Reedik Mägi,John R. B. Perry,Tune H. Pers,Qibin Qi,Marianna Sanna,Marianna Sanna,Ellen M. Schmidt,William R. Scott,William R. Scott,Dmitry Shungin,Dmitry Shungin,Alexander Teumer,Anna A. E. Vinkhuyzen,Ryan W. Walker,Harm-Jan Westra,Mingfeng Zhang,Weihua Zhang,Weihua Zhang,Jing Hua Zhao,Zhihong Zhu,Uzma Afzal,Uzma Afzal,Tarunveer S. Ahluwalia,Stephan J. L. Bakker,Claire Bellis,Amélie Bonnefond,Amélie Bonnefond,Katja Borodulin,Aron S. Buchman,Tommy Cederholm,Audrey C. Choh,Hyung Jin Choi,Joanne E. Curran,Lisette C. P. G. M. de Groot,Philip L. De Jager,Philip L. De Jager,Philip L. De Jager,Rosalie A. M. Dhonukshe-Rutten,Anke W. Enneman,Elodie Eury,Elodie Eury,Daniel S. Evans,Tom Forsén,Nele Friedrich,Frédéric Fumeron,Melissa E. Garcia,Simone Gärtner,Bok-Ghee Han,Aki S. Havulinna,Caroline Hayward,Dena G. Hernandez,Hans L. Hillege,Till Ittermann,Jack W. Kent,Ivana Kolcic,Tiina Laatikainen,Tiina Laatikainen,Jari Lahti,Irene Mateo Leach,Christine G. Lee,Christine G. Lee,Jong-Young Lee,Tian Liu,Youfang Liu,Stéphane Lobbens,Stéphane Lobbens,Marie Loh,Marie Loh,Leo-Pekka Lyytikäinen,Carolina Medina-Gomez,Karl Michaëlsson,Mike A. Nalls,Carrie M. Nielson,Laticia Oozageer,Laura Pascoe,Lavinia Paternoster,Ozren Polasek,Ozren Polasek,Samuli Ripatti,Samuli Ripatti,Mark A. Sarzynski,Chan Soo Shin,Nina Smolej Narančić,Dominik Spira,Priya Srikanth,Elisabeth Steinhagen-Thiessen,Yun Ju Sung,Karin M. A. Swart,Karin M. A. Swart,Leena Taittonen,Toshiko Tanaka,Emmi Tikkanen,Nathalie van der Velde,Natasja M. van Schoor,Natasja M. van Schoor,Niek Verweij,Alan F. Wright,Lei Yu,Joseph M. Zmuda,Niina Eklund,Terrence Forrester,Niels Grarup,Anne U. Jackson,Kati Kristiansson,Kati Kristiansson,Teemu Kuulasmaa,Johanna Kuusisto,Peter Lichtner,Jian'an Luan,Anubha Mahajan,Satu Männistö,Cameron D. Palmer,Cameron D. Palmer,Janina S. Ried,Robert A. Scott,Alena Stančáková,Peter Wagner,Peter Wagner,Ayse Demirkan,Angela Döring,Vilmundur Gudnason,Douglas P. Kiel,Brigitte Kühnel,Massimo Mangino,Barbara McKnight,Barbara McKnight,Cristina Menni,Jeffrey R. O'Connell,Ben A. Oostra,Alan R. Shuldiner,Alan R. Shuldiner,Kijoung Song,Liesbeth Vandenput,Cornelia M. van Duijn,Peter Vollenweider,Charles C. White,Michael Boehnke,Yvonne Boettcher,Richard S. Cooper,Nita G. Forouhi,Christian Gieger,Harald Grallert,Aroon D. Hingorani,Torben Jørgensen,Torben Jørgensen,Pekka Jousilahti,Mika Kivimäki,Meena Kumari,Markku Laakso,Claudia Langenberg,Allan Linneberg,Amy Luke,Colin A. McKenzie,Aarno Palotie,Aarno Palotie,Aarno Palotie,Oluf Pedersen,Annette Peters,Konstantin Strauch,Bamidele O. Tayo,Nicholas J. Wareham,David A. Bennett,Lars Bertram,Lars Bertram,John Blangero,Matthias Blüher,Claude Bouchard,Harry Campbell,Nam H. Cho,Steven R. Cummings,Stefan A. Czerwinski,Ilja Demuth,Rahel Eckardt,Johan G. Eriksson,Johan G. Eriksson,Luigi Ferrucci,Oscar H. Franco,Philippe Froguel,Philippe Froguel,Ron T. Gansevoort,Torben Hansen,Torben Hansen,Tamara B. Harris,Nicholas D. Hastie,Markku Heliövaara,Albert Hofman,Joanne M. Jordan,Antti Jula,Mika Kähönen,Eero Kajantie,Eero Kajantie,Eero Kajantie,Paul Knekt,Seppo Koskinen,Peter Kovacs,Terho Lehtimäki,Lars Lind,Yongmei Liu,Eric S. Orwoll,Clive Osmond,Markus Perola,Markus Perola,Louis Pérusse,Olli T. Raitakari,Olli T. Raitakari,Tuomo Rankinen,Dabeeru C. Rao,Treva Rice,Fernando Rivadeneira,Igor Rudan,Veikko Salomaa,Thorkild I. A. Sørensen,Michael Stumvoll,Anke Tönjes,Bradford Towne,Gregory J. Tranah,Angelo Tremblay,André G. Uitterlinden,Pim van der Harst,Erkki Vartiainen,Jorma S. A. Viikari,Veronique Vitart,Marie-Claude Vohl,Henry Völzke,Mark Walker,Mark Walker,Henri Wallaschofski,Sarah H Wild,James F. Wilson,Loic Yengo,Loic Yengo,D. Timothy Bishop,Ingrid B. Borecki,Ingrid B. Borecki,John C. Chambers,John C. Chambers,John C. Chambers,L. Adrienne Cupples,Abbas Dehghan,Panos Deloukas,Panos Deloukas,Panos Deloukas,Ghazaleh Fatemifar,Caroline S. Fox,Terrence S. Furey,Lude Franke,Jiali Han,David J. Hunter,Juha Karjalainen,Fredrik Karpe,Robert C. Kaplan,Jaspal S. Kooner,Jaspal S. Kooner,Jaspal S. Kooner,Mark I. McCarthy,Joanne M. Murabito,Andrew P. Morris,Andrew P. Morris,Julia A. Newton Bishop,Kari E. North,Claes Ohlsson,Ken K. Ong,Inga Prokopenko,J. Brent Richards,Eric E. Schadt,Tim D. Spector,Elisabeth Widen,Cristen J. Willer,Jian Yang,Erik Ingelsson,Erik Ingelsson,Erik Ingelsson,Karen L. Mohlke,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,John Andrew Pospisilik,M. Carola Zillikens,Cecilia M. Lindgren,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Ruth J. F. Loos +311 more
TL;DR: The loci more strongly associated with BF% showed distinct cross-phenotype association signatures with a range of cardiometabolic traits revealing new insights in the link between adiposity and disease risk.
Journal ArticleDOI
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2.
Fred A. Wright,Lisa J. Strug,Vishal K. Doshi,Clayton W. Commander,Scott M. Blackman,Lei Sun,Yves Berthiaume,David J. Cutler,Andreea L. Cojocaru,J. Michael Collaco,Mary Corey,Ruslan Dorfman,Katrina A.B. Goddard,Deanna M. Green,Jack W. Kent,Ethan M. Lange,Seunggeun Lee,Weili Li,Jingchun Luo,Gregory Mayhew,Kathleen M. Naughton,Rhonda G. Pace,Peter D. Paré,Johanna M. Rommens,Andrew J. Sandford,Jaclyn R. Stonebraker,Wei Sun,Chelsea Taylor,Lori L. Vanscoy,Fei Zou,John Blangero,Julian Zielenski,Wanda K. O'Neal,Mitchell L. Drumm,Peter R. Durie,Michael R. Knowles,Garry R. Cutting +36 more
TL;DR: The authors' findings provide insight into the causes of variation in lung disease severity in cystic fibrosis and suggest new therapeutic targets for this life-limiting disorder.