M
Marion Cremer
Researcher at Ludwig Maximilian University of Munich
Publications - 68
Citations - 6325
Marion Cremer is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Chromatin & Chromosome Territory. The author has an hindex of 33, co-authored 67 publications receiving 5939 citations. Previous affiliations of Marion Cremer include Heidelberg University & Technische Universität München.
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Journal ArticleDOI
Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions
TL;DR: This work has shown that the dynamic nature of the positioning of genetic material in the nuclear space and the higher-order architecture of the nucleus are integrated is essential to the overall understanding of gene regulation.
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Chromosome territories--a functional nuclear landscape.
TL;DR: This work has shown that chromosomes in the cell nucleus are organized as chromosome territories, and present models of chromosome territory architecture differ widely with respect to the possible functional implications of dynamic changes of this architecture during the cell cycle and terminal cell differentiation.
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Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates.
Hideyuki Tanabe,Stefan Müller,Michaela Neusser,Johann von Hase,Enzo Calcagno,Marion Cremer,Irina Solovei,Christoph Cremer,Thomas Cremer +8 more
TL;DR: The data demonstrate that gene-density-correlated radial chromatin arrangements were conserved during higher-primate genome evolution, irrespective of the major karyotypic rearrangements that occurred in different phylogenetic lineages.
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Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells.
Marion Cremer,Johann von Hase,Tanja Volm,Alessandro Brero,Gregor Kreth,Joachim Walter,Christine Fischer,Irina Solovei,Christoph Cremer,Thomas Cremer +9 more
TL;DR: It is concluded that nuclear functions in the studied cell types may not require reproducible side-by-side arrangements of specific homologous or non-homologous CTs, and that presently unknown factors may play a decisive role to enforce the different radial arrangements of large and small CTs observed in ellipsoid and spherical human cell nuclei.
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Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages
TL;DR: Long-term live-cell studies using a HeLa cell line with GFP-tagged chromatin concluded that CT arrangements were stably maintained from mid G1 to late G2/early prophase, whereas major changes of CT neighborhoods occurred from one cell cycle to the next.