B
Bente Finsen
Researcher at University of Southern Denmark
Publications - 181
Citations - 18954
Bente Finsen is an academic researcher from University of Southern Denmark. The author has contributed to research in topics: Microglia & Dentate gyrus. The author has an hindex of 50, co-authored 176 publications receiving 15424 citations. Previous affiliations of Bente Finsen include Aarhus University & University of Freiburg.
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Journal ArticleDOI
Natural RNA circles function as efficient microRNA sponges
Thomas B. Hansen,Trine I. Jensen,Bettina Hjelm Clausen,Jesper B. Bramsen,Bente Finsen,Christian Kroun Damgaard,Jørgen Kjems +6 more
TL;DR: This study serves as the first functional analysis of a naturally expressed circular RNA, ciRS-7, which contains more than 70 selectively conserved miRNA target sites, and is highly and widely associated with Argonaute proteins in a miR-7-dependent manner.
Journal ArticleDOI
Neuroinflammation in Alzheimer's disease
Michael T. Heneka,Monica J. Carson,Joseph El Khoury,Gary E. Landreth,Frederic Brosseron,Douglas L. Feinstein,Andreas H. Jacobs,Tony Wyss-Coray,Tony Wyss-Coray,Javier Vitorica,Richard M. Ransohoff,Karl Herrup,Sally A. Frautschy,Bente Finsen,Guy C. Brown,Alexei Verkhratsky,Alexei Verkhratsky,Alexei Verkhratsky,Koji Yamanaka,Jari Koistinaho,Eicke Latz,Eicke Latz,Annett Halle,Gabor C. Petzold,Terrence Town,Dave Morgan,Mari L. Shinohara,V. Hugh Perry,Clive Holmes,Clive Holmes,Nicolas G. Bazan,David J. Brooks,Stéphane Hunot,Bertrand Joseph,Nikolaus Deigendesch,Olga Garaschuk,Erik Boddeke,Charles A. Dinarello,John C.S. Breitner,Greg M. Cole,Douglas T. Golenbock,Markus P. Kummer +41 more
TL;DR: Genome-wide analysis suggests that several genes that increase the risk for sporadic Alzheimer's disease encode factors that regulate glial clearance of misfolded proteins and the inflammatory reaction.
Journal ArticleDOI
Inflammatory cytokines in experimental and human stroke
TL;DR: The fact that TNF and IL-1, and suppossedly also IL-6, are produced by microglia within the therapeutic window place these cells centrally in potential future stroke therapy, in the context of suggestions that neuronal sensitivity to ischemia may be modulated by cytokines.
Journal ArticleDOI
Spatio-temporal regulation of circular RNA expression during porcine embryonic brain development
Morten T. Venø,Thomas B. Hansen,Susanne T. Venø,Bettina Hjelm Clausen,Manuela Grebing,Bente Finsen,Ida Elisabeth Holm,Jørgen Kjems +7 more
TL;DR: It is demonstrated that circRNAs are highly abundant and dynamically expressed in a spatio-temporal manner in porcine fetal brain, suggesting important functions during mammalian brain development.
Journal ArticleDOI
Microglia protect neurons against ischemia by synthesis of tumor necrosis factor.
Kate Lykke Lambertsen,Bettina Hjelm Clausen,Alicia A. Babcock,Rikke Gregersen,Christina Fenger,Helle Hvilsted Nielsen,Laila Skov Haugaard,Martin Wirenfeldt,Marianne Nielsen,Frederik Dagnæs-Hansen,Horst Bluethmann,Nils J. Færgeman,Michael Meldgaard,Tomas Deierborg,Bente Finsen +14 more
TL;DR: It is reported that TNF deficiency is associated with reduced microglial population size and Toll-like receptor 2 expression in unmanipulated brain, which might also influence the neuronal response to injury.