C
Chantal Chabo
Researcher at French Institute of Health and Medical Research
Publications - 14
Citations - 6891
Chantal Chabo is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Adipose tissue & Inflammation. The author has an hindex of 11, co-authored 14 publications receiving 5838 citations. Previous affiliations of Chantal Chabo include University of Toulouse & Paul Sabatier University.
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Journal ArticleDOI
Metabolic endotoxemia initiates obesity and insulin resistance
Patrice D. Cani,Jacques Amar,Miguel A. Iglesias,Marjorie Poggi,Claude Knauf,Delphine Bastelica,Audrey M. Neyrinck,Francesca Fava,Kieran Tuohy,Chantal Chabo,Aurélie Waget,Evelyne Delmée,Béatrice Cousin,Thierry Sulpice,Bernard Chamontin,Jean Ferrières,Jean-François Tanti,Glenn R. Gibson,Louis Casteilla,Nathalie M. Delzenne,Marie-Christine Alessi,Rémy Burcelin +21 more
TL;DR: It is concluded that the LPS/CD14 system sets the tone of insulin sensitivity and the onset of diabetes and obesity and lowering plasma LPS concentration could be a potent strategy for the control of metabolic diseases.
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Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment
Jacques Amar,Chantal Chabo,Aurélie Waget,Pascale Klopp,Christelle Vachoux,Luis G. Bermúdez-Humarán,Natalia F. Smirnova,Mathieu Bergé,Mathieu Bergé,Thierry Sulpice,Sampo J. Lahtinen,Arthur C. Ouwehand,Philippe Langella,Nina Rautonen,Philippe J. Sansonetti,Rémy Burcelin +15 more
TL;DR: It is demonstrated that the early onset of HFD‐induced hyperglycemia is characterized by an increased bacterial translocation from intestine towards tissues, fuelling a continuous metabolic bacteremia, which could represent new therapeutic targets.
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Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept
Jacques Amar,Matteo Serino,Céline Lange,Chantal Chabo,Jason S. Iacovoni,Stanislas Mondot,Patricia Lepage,Christophe Klopp,Jérôme Mariette,Olivier Bouchez,L. Perez,Michael Courtney,Michel Marre,Pascale Klopp,Olivier Lantieri,Joël Doré,Marie-Aline Charles,B. Balkau,Rémy Burcelin +18 more
TL;DR: 16S rDNA was shown to be an independent marker of the risk of diabetes, evidence for the concept that tissue bacteria are involved in the onset of diabetes in humans.
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Gut microbiota and diabetes: from pathogenesis to therapeutic perspective
Rémy Burcelin,Rémy Burcelin,Matteo Serino,Matteo Serino,Chantal Chabo,Chantal Chabo,Vincent Blasco-Baque,Vincent Blasco-Baque,Jacques Amar +8 more
TL;DR: Much more need to be uncovered in order to identify first, new predictive biomarkers so that preventive strategies based on pre- and probiotics, and second, new therapeutic strategies against the cause rather than the consequence of hyperglycemia and body weight gain are found.
Journal ArticleDOI
Blood microbiota dysbiosis is associated with the onset of cardiovascular events in a large general population: the D.E.S.I.R. study.
Jacques Amar,Céline Lange,Gaëlle Payros,Céline Garret,Chantal Chabo,Olivier Lantieri,Michael Courtney,Michel Marre,Marie-Aline Charles,Beverley Balkau,Rémy Burcelin +10 more
TL;DR: Pbac and Eubac were shown to be independent markers of the risk of cardiovascular disease, evidence for the new concept of the role played by blood microbiota dysbiosis on atherothrombotic disease.