Nobuhito Kashiwagi

TL;DR: Based on the results, it is believed that in patients with active severe UC, patients who are refractory to conventional drugs, granulocyte and monocyte adsorption apheresis is a useful adjunct to conventional therapy.

TL;DR: In peripheral blood treated with the G-1 beads or peripheral blood from patients with active ulcerative colitis following granulocyte and monocyte adsorption apheresis, a significant suppression of proinflammatory cytokines and the number of CD10-negative premature granulocytes increased, indicating increased turnover of these cells in the circulation.

TL;DR: CA beads might be an appropriate biomaterial for inducing extracorporeal immunomodulation as a treatment for auto‐immune diseases which are associated with pathological leukocyte activity.

TL;DR: In this article, a dramatic change in glycosylation was induced on CD8+T cells from HIV infected patients, which correlated with the progression of the disease and increased as the disease progressed with the ongoing impairment of immune function.

TL;DR: In this article, a method of treating inflammatory diseases, in which peripheral blood of a patient suffering from an inflammatory disease is made into contact with a carrier whose affinity for inflammation-associated cells is higher than that for lymphocytes, and the thus-obtained treated blood is returned to the patient.