Y
Yukio Nagamachi
Researcher at Gunma University
Publications - 160
Citations - 2630
Yukio Nagamachi is an academic researcher from Gunma University. The author has contributed to research in topics: Cancer & Cinchophen. The author has an hindex of 27, co-authored 160 publications receiving 2575 citations. Previous affiliations of Yukio Nagamachi include Shinshu University.
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Journal ArticleDOI
Safety and efficacy of granulocyte and monocyte adsorption apheresis in patients with active ulcerative colitis: a multicenter study.
Takashi Shimoyama,Koji Sawada,Nobuo Hiwatashi,Toshio Sawada,Kei Matsueda,Akihiro Munakata,Hitoshi Asakura,Takao Tanaka,Reiji Kasukawa,Ken Kimura,Yasuo Suzuki,Yukio Nagamachi,Tetsuichiro Muto,Hirokazu Nagawa,Bunei Iizuka,Shozo Baba,Masaru Nasu,Tatsuji Kataoka,Nobuhito Kashiwagi,Abby R. Saniabadi +19 more
TL;DR: Based on the results, it is believed that in patients with active severe UC, patients who are refractory to conventional drugs, granulocyte and monocyte adsorption apheresis is a useful adjunct to conventional therapy.
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Immuno-localization of H+/peptide cotransporter in rat digestive tract.
Hiroshi Ogihara,Hideyuki Saito,Bo-Chul Shin,Tomohiro Terada,Seiichi Takenoshita,Yukio Nagamachi,Ken-ichi Inui,Kuniaki Takata +7 more
TL;DR: Observations show that PepT1 is specific to the brush border of the differentiated absorptive epithelial cells and suggest that H+-coupled uptake of small peptides and peptide-like drugs occurs at the apical membrane of these cells in the small intestine.
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Lung carcinogenesis and formation of 8-hydroxy-deoxyguanosine in mice by diesel exhaust particles.
Takamichi Ichinose,Y Yajima,Makoto Nagashima,Seiichi Takenoshita,Yukio Nagamachi,Masaru Sagai +5 more
TL;DR: The results suggest that the induction of oxidative DNA damage may be an important factor in the initiation of DEP-induced lung carcinogenesis, and that beta-carotene and high dietary fat may play a role in the regulation of tumour development via modulation of the formation of 8-OHdG.
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Genetic analysis of obese diabetes in the TSOD mouse.
Isao Hirayama,Zhaohong Yi,Sumiko Izumi,Ichiro Arai,Wataru Suzuki,Yukio Nagamachi,Hiroyuki Kuwano,Toshiyuki Takeuchi,Tetsuro Izumi +8 more
TL;DR: It is indicated that hyperglycemia and obesity are clearly controlled by distinct combinations of genetic loci in this mouse model and provides insights into the genetic basis of common forms of human type 2 diabetes with obesity.
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Peptide transporter in the rat small intestine: ultrastructural localization and the effect of starvation and administration of amino acids.
TL;DR: Observations show that peptide transporter-1 is specific to the microvillous plasma membrane and that its expression is regulated by the nutritional condition.