J
Jon D. Weingart
Researcher at Johns Hopkins University School of Medicine
Publications - 140
Citations - 12699
Jon D. Weingart is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Glioma & Medicine. The author has an hindex of 51, co-authored 129 publications receiving 10836 citations. Previous affiliations of Jon D. Weingart include Johns Hopkins University & Duke University.
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Journal ArticleDOI
Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
Chetan Bettegowda,Chetan Bettegowda,Mark Sausen,Rebecca J. Leary,Isaac Kinde,Yuxuan Wang,Nishant Agrawal,Nishant Agrawal,Bjarne Bartlett,Bjarne Bartlett,Hao Wang,Brandon Luber,Rhoda M. Alani,Emmanuel S. Antonarakis,Nilofer S. Azad,Alberto Bardelli,Henry Brem,John L. Cameron,Clarence Lee,Leslie A. Fecher,Leslie A. Fecher,Gary L. Gallia,Peter Gibbs,Dung T. Le,Dung T. Le,Robert L. Giuntoli,Michael Goggins,Michael D. Hogarty,Matthias Holdhoff,Seung-Mo Hong,Seung-Mo Hong,Yuchen Jiao,Hartmut Juhl,Jenny J. Kim,Giulia Siravegna,Daniel A. Laheru,Calogero Lauricella,Michael Lim,Evan J. Lipson,Suely Kazue Nagahashi Marie,George J. Netto,Kelly S. Oliner,Alessandro Olivi,Louise Olsson,Gregory J. Riggins,Andrea Sartore-Bianchi,Kerstin Schmidt,le-Ming Shih,Sueli Mieko Oba-Shinjo,Salvatore Siena,Dan Theodorescu,Jeanne Tie,Timothy T. Harkins,Silvio Veronese,Tian Li Wang,Jon D. Weingart,Christopher L. Wolfgang,Laura D. Wood,Dongmei Xing,Ralph H. Hruban,Jian Wu,Peter J. Allen,C. Max Schmidt,Michael A. Choti,Victor E. Velculescu,Kenneth W. Kinzler,Bert Vogelstein,Nickolas Papadopoulos,Luis A. Diaz,Luis A. Diaz +69 more
TL;DR: The ability of circulating tumor DNA (ctDNA) to detect tumors in 640 patients with various cancer types was evaluated and suggested that ctDNA is a broadly applicable, sensitive, and specific biomarker that can be used for a variety of clinical and research purposes.
Journal ArticleDOI
Independent association of extent of resection with survival in patients with malignant brain astrocytoma: Clinical article
Matthew J. McGirt,Kaisorn L. Chaichana,Muraya Gathinji,Frank J. Attenello,Khoi D. Than,Alessandro Olivi,Jon D. Weingart,Henry Brem,Alf redo Quiñones-Hinojosa +8 more
TL;DR: In the authors' experience with both primary and secondary resection of malignant brain astrocytomas, increasing extent of resection was associated with improved survival independent of age, degree of disability, WHO grade, or subsequent treatment modalities used.
Journal ArticleDOI
Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas.
Matthew J. McGirt,Kaisorn L. Chaichana,Frank J. Attenello,Jon D. Weingart,Khoi D. Than,Peter C. Burger,Alessandro Olivi,Henry Brem,Alfredo Quiñones-Hinojosa +8 more
TL;DR: GTR was associated with a delay in tumor progression and malignant degeneration as well as improved OS independent of age, degree of disability, histological subtype, or revision versus primary resection.
Journal ArticleDOI
Establishing percent resection and residual volume thresholds affecting survival and recurrence for patients with newly diagnosed intracranial glioblastoma
Kaisorn L. Chaichana,Ignacio Jusué-Torres,Rodrigo Navarro-Ramirez,Shaan M. Raza,Maria Pascual-Gallego,Aly Ibrahim,Marta Hernandez-Hermann,Luis Gomez,Xiaobu Ye,Jon D. Weingart,Alessandro Olivi,Jaishri O. Blakeley,Gary L. Gallia,Michael Lim,Henry Brem,Alfredo Quiñones-Hinojosa +15 more
TL;DR: This study shows for the first time that both EOR and RV are significantly associated with survival and recurrence, where the thresholds are 70% and 5 cm(3), respectively.
Journal ArticleDOI
Association of surgically acquired motor and language deficits on overall survival after resection of glioblastoma multiforme
Matthew J. McGirt,Debraj Mukherjee,Kaisorn L. Chaichana,Khoi D. Than,Jon D. Weingart,Alfredo Quiñones-Hinojosa +5 more
TL;DR: The development of new perioperative motor or language deficits was associated with decreased overall survival despite similar extent of resection and adjuvant therapy, and results suggest that these surgical morbidities may also affect survival.