scispace - formally typeset
J

Jian Wu

Researcher at Fudan University

Publications -  1210
Citations -  48846

Jian Wu is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 82, co-authored 871 publications receiving 39968 citations. Previous affiliations of Jian Wu include National Institutes of Health & Soochow University (Suzhou).

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

Chetan Bettegowda, +69 more
- 19 Feb 2014 - 
TL;DR: The ability of circulating tumor DNA (ctDNA) to detect tumors in 640 patients with various cancer types was evaluated and suggested that ctDNA is a broadly applicable, sensitive, and specific biomarker that can be used for a variety of clinical and research purposes.
Journal ArticleDOI

The genome of the mesopolyploid crop species Brassica rapa

Xiaowu Wang, +116 more
- 01 Oct 2011 - 
TL;DR: The annotation and analysis of the draft genome sequence of Brassica rapa accession Chiifu-401-42, a Chinese cabbage, and used Arabidopsis thaliana as an outgroup for investigating the consequences of genome triplication, such as structural and functional evolution.
Journal ArticleDOI

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

Luis A. Diaz, +15 more
- 28 Jun 2012 - 
TL;DR: Results suggest that the emergence of KRAS mutations is a mediator of acquired resistance to EGFR blockade and that these mutations can be detected in a non-invasive manner, which explains why solid tumours develop resistance to targeted therapies in a highly reproducible fashion.
Journal ArticleDOI

The genome of the cucumber, Cucumis sativus L.

Sanwen Huang, +95 more
- 01 Dec 2009 - 
TL;DR: This study establishes that five of the cucumber's seven chromosomes arose from fusions of ten ancestral chromosomes after divergence from Cucumis melo, and identifies 686 gene clusters related to phloem function.