J
Joseph D. Lamplot
Researcher at University of Chicago
Publications - 20
Citations - 1274
Joseph D. Lamplot is an academic researcher from University of Chicago. The author has contributed to research in topics: Wnt signaling pathway & Cellular differentiation. The author has an hindex of 11, co-authored 15 publications receiving 1049 citations.
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Journal ArticleDOI
Wnt signaling in bone formation and its therapeutic potential for bone diseases
Jeong Hwan Kim,Xing Liu,Jinhua Wang,Xiang Chen,Hongyu Zhang,Stephanie H. Kim,Jing Cui,Ruidong Li,Wenwen Zhang,Yuhan Kong,Jiye Zhang,Wei Shui,Joseph D. Lamplot,Mary Rose Rogers,Chen Zhao,Ning Wang,Prashant Rajan,Justin Tomal,Joseph Statz,Ningning Wu,Hue H. Luu,Rex C. Haydon,Tong-Chuan He +22 more
TL;DR: The present review discusses the role of the Wnt signaling pathway in osteogenesis and examines its targeted therapeutic potential and indicates it requires cautious approach due to risks of tumorigenesis.
Journal ArticleDOI
BMP signaling in mesenchymal stem cell differentiation and bone formation.
Maureen Beederman,Joseph D. Lamplot,Guoxin Nan,Jinhua Wang,Xing Liu,Liangjun Yin,Ruidong Li,Wei Shui,Hongyu Zhang,Stephanie H. Kim,Wenwen Zhang,Jiye Zhang,Yuhan Kong,Sahitya K. Denduluri,Mary Rose Rogers,Abdullah Pratt,Rex C. Haydon,Hue H. Luu,Jovito Angeles,Lewis L. Shi,Tong-Chuan He +20 more
TL;DR: Current knowledge of BMP-mediated osteogenesis is summarized, with a focus on BMP9, by presenting recently completed work which may help to further elucidate these pathways.
Journal ArticleDOI
Multimodal pain management in total knee arthroplasty: a prospective randomized controlled trial.
TL;DR: The multimodal group had lower VAS scores, fewer adverse effects, lower narcotic usage, higher satisfaction scores and earlier times to physical therapy milestones.
Journal ArticleDOI
BMP-9 induced osteogenic differentiation of mesenchymal stem cells: molecular mechanism and therapeutic potential.
Gaurav Luther,Eric R. Wagner,Gao-Hui Zhu,Quan Kang,Qing Luo,Joseph D. Lamplot,Yang Bi,Xiaoji Luo,Jinyong Luo,Chad M. Teven,Qiong Shi,Stephanie H. Kim,Jian-Li Gao,Enyi Huang,Ke Yang,Richard Rames,Xing Liu,Mi Li,Ning Hu,Hong Liu,Yuxi Su,Liang Chen,Bai-Cheng He,Guo-Wei Zuo,Zhong-Liang Deng,Russell R. Reid,Hue H. Luu,Rex C. Haydon,Tong-Chuan He +28 more
TL;DR: The results suggest that BMP-9 should be explored as an effective bone regeneration agent, especially in combination with adjuvant therapies, for clinical applications such as large segmental bony defects, non-union fractures, and/or spinal fusions.
Journal ArticleDOI
BMP9 signaling in stem cell differentiation and osteogenesis.
Joseph D. Lamplot,Jiaqiang Qin,Guoxin Nan,Jinhua Wang,Xing Liu,Liangjun Yin,Justin Tomal,Ruidong Li,Wei Shui,Hongyu Zhang,Stephanie H. Kim,Wenwen Zhang,Jiye Zhang,Yuhan Kong,Sahitya K. Denduluri,Mary Rose Rogers,Abdullah Pratt,Rex C. Haydon,Hue H. Luu,Jovito Angeles,Lewis L. Shi,Tong-Chuan He +21 more
TL;DR: In this paper, the authors summarize the current knowledge of BMP9-mediated osteogenesis by presenting recently completed work which may help us to further elucidate these pathways, and they conclude that BMP-9 is known to be a potent osteogenic factor, it also influences several other pathways including cancer development, angiogenesis and myogenesis.