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Ning Wang
Researcher at University of Chicago
Publications - 16
Citations - 1069
Ning Wang is an academic researcher from University of Chicago. The author has contributed to research in topics: Stem cell & Mesenchymal stem cell. The author has an hindex of 14, co-authored 16 publications receiving 934 citations. Previous affiliations of Ning Wang include Third Military Medical University.
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Journal ArticleDOI
Wnt signaling in bone formation and its therapeutic potential for bone diseases
Jeong Hwan Kim,Xing Liu,Jinhua Wang,Xiang Chen,Hongyu Zhang,Stephanie H. Kim,Jing Cui,Ruidong Li,Wenwen Zhang,Yuhan Kong,Jiye Zhang,Wei Shui,Joseph D. Lamplot,Mary Rose Rogers,Chen Zhao,Ning Wang,Prashant Rajan,Justin Tomal,Joseph Statz,Ningning Wu,Hue H. Luu,Rex C. Haydon,Tong-Chuan He +22 more
TL;DR: The present review discusses the role of the Wnt signaling pathway in osteogenesis and examines its targeted therapeutic potential and indicates it requires cautious approach due to risks of tumorigenesis.
Journal ArticleDOI
BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells
Ning Hu,Dianming Jiang,Enyi Huang,Enyi Huang,Xing Liu,Xing Liu,Ruidong Li,Ruidong Li,Xi Liang,Xi Liang,Stephanie H. Kim,Xiang Chen,Xiang Chen,Jian-Li Gao,Jian-Li Gao,Hongyu Zhang,Hongyu Zhang,Wenwen Zhang,Wenwen Zhang,Yuhan Kong,Yuhan Kong,Jiye Zhang,Jiye Zhang,Jinhua Wang,Jinhua Wang,Wei Shui,Wei Shui,Xiaoji Luo,Xiaoji Luo,Bo Liu,Bo Liu,Jing Cui,Jing Cui,Mary Rose Rogers,Jikun Shen,Chen Zhao,Chen Zhao,Ning Wang,Ning Wang,Ningning Wu,Ningning Wu,Hue H. Luu,Rex C. Haydon,Tong-Chuan He,Wei Huang +44 more
TL;DR: These findings should not only expand the understanding of the molecular basis behind BMP9-regulated osteoblastic lineage-specific differentiation, but also provide an opportunity to harness the B MP9-induced synergy between osteogenic and angiogenic signaling pathways in regenerative medicine.
Journal ArticleDOI
Adenovirus-mediated gene transfer in mesenchymal stem cells can be significantly enhanced by the cationic polymer polybrene.
Chen Zhao,Ningning Wu,Fang Deng,Hongmei Zhang,Ning Wang,Wenwen Zhang,Xian Chen,Sheng Wen,Junhui Zhang,Liangjun Yin,Zhan Liao,Zhonglin Zhang,Qian Zhang,Zhengjian Yan,Wei Liu,Di Wu,Jixing Ye,Youlin Deng,Guolin Zhou,Hue H. Luu,Rex C. Haydon,Weike Si,Tong-Chuan He +22 more
TL;DR: Results demonstrate that Polybrene should be routinely used as a safe, effective and inexpensive augmenting agent for adenovirus-mediated gene transfer in MSCs, as well as other types of mammalian cells.
Journal ArticleDOI
Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways
Jian-Li Gao,Gui-Yuan Lv,Bai-Cheng He,Bing-Qiang Zhang,Hongyu Zhang,Ning Wang,Chong-Zhi Wang,Wei Du,Chun-Su Yuan,Tong-Chuan He +9 more
TL;DR: The results suggest that the antic cancer activity of PPD in colon cancer cells may be mediated through targeting NF-κB, JNK and MAPK/ERK signaling pathways, although the detailed mechanisms underlying the anticancer mode of P PD action need to be fully elucidated.
Journal ArticleDOI
Cross-talk between EGF and BMP9 signalling pathways regulates the osteogenic differentiation of mesenchymal stem cells
Xing Liu,Jiaqiang Qin,Jiaqiang Qin,Qing Luo,Qing Luo,Yang Bi,Yang Bi,Gao-Hui Zhu,Gao-Hui Zhu,Wei Jiang,Stephanie H. Kim,Mi Li,Mi Li,Yuxi Su,Yuxi Su,Guoxin Nan,Guoxin Nan,Jing Cui,Jing Cui,Wenwen Zhang,Wenwen Zhang,Ruidong Li,Ruidong Li,Xiang Chen,Xiang Chen,Yuhan Kong,Yuhan Kong,Jiye Zhang,Jiye Zhang,Jinhua Wang,Jinhua Wang,Mary Rose Rogers,Hongyu Zhang,Hongyu Zhang,Wei Shui,Wei Shui,Chen Zhao,Chen Zhao,Ning Wang,Ning Wang,Xi Liang,Xi Liang,Ningning Wu,Ningning Wu,Yunfeng He,Yunfeng He,Hue H. Luu,Rex C. Haydon,Lewis L. Shi,Tingyu Li,Tong-Chuan He,Tong-Chuan He,Ming Li +52 more
TL;DR: It is found that EGF potentiates BMP9‐induced early and late osteogenic markers of MSCs in vitro, which can be effectively blunted by EGFR inhibitors Gefitinib and Erlotinib or receptor tyrosine kinase inhibitors AG‐1478 and AG‐494 in a dose‐ and time‐dependent manner.