J
Joseph Statz
Researcher at University of Chicago
Publications - 2
Citations - 373
Joseph Statz is an academic researcher from University of Chicago. The author has contributed to research in topics: Wnt signaling pathway & LRP6. The author has an hindex of 2, co-authored 2 publications receiving 319 citations.
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Journal ArticleDOI
Wnt signaling in bone formation and its therapeutic potential for bone diseases
Jeong Hwan Kim,Xing Liu,Jinhua Wang,Xiang Chen,Hongyu Zhang,Stephanie H. Kim,Jing Cui,Ruidong Li,Wenwen Zhang,Yuhan Kong,Jiye Zhang,Wei Shui,Joseph D. Lamplot,Mary Rose Rogers,Chen Zhao,Ning Wang,Prashant Rajan,Justin Tomal,Joseph Statz,Ningning Wu,Hue H. Luu,Rex C. Haydon,Tong-Chuan He +22 more
TL;DR: The present review discusses the role of the Wnt signaling pathway in osteogenesis and examines its targeted therapeutic potential and indicates it requires cautious approach due to risks of tumorigenesis.
Journal ArticleDOI
Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells.
Enyi Huang,Gao-Hui Zhu,Gao-Hui Zhu,Wei Jiang,Ke Yang,Ke Yang,Yanhong Gao,Yanhong Gao,Qing Luo,Qing Luo,Jian-Li Gao,Jian-Li Gao,Stephanie H. Kim,Xing Liu,Xing Liu,Mi Li,Mi Li,Qiong Shi,Qiong Shi,Ning Hu,Ning Hu,Linyuan Wang,Hong Liu,Hong Liu,Jing Cui,Jing Cui,Wenwen Zhang,Wenwen Zhang,Ruidong Li,Ruidong Li,Xiang Chen,Xiang Chen,Yuhan Kong,Yuhan Kong,Jiye Zhang,Jiye Zhang,Jinhua Wang,Jinhua Wang,Jikun Shen,Yang Bi,Yang Bi,Joseph Statz,Bai-Cheng He,Bai-Cheng He,Jinyong Luo,Jinyong Luo,Huicong Wang,Feng Xiong,Hue H. Luu,Rex C. Haydon,Li Yang,Tong-Chuan He,Tong-Chuan He +52 more
TL;DR: Bone morphogenic protein 9 (BMP9) is identified as one of the most osteogenic BMPs in MMCs by regulating a distinct set of downstream mediators and it is conceivable that the BMP9‐GH‐IGF axis may be exploited as an innovative strategy to enhance osteogenesis in regenerative medicine.