P
Prashant Rajan
Researcher at Miami University
Publications - 4
Citations - 404
Prashant Rajan is an academic researcher from Miami University. The author has contributed to research in topics: RNA & Nucleic acid structure. The author has an hindex of 3, co-authored 4 publications receiving 346 citations.
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Wnt signaling in bone formation and its therapeutic potential for bone diseases
Jeong Hwan Kim,Xing Liu,Jinhua Wang,Xiang Chen,Hongyu Zhang,Stephanie H. Kim,Jing Cui,Ruidong Li,Wenwen Zhang,Yuhan Kong,Jiye Zhang,Wei Shui,Joseph D. Lamplot,Mary Rose Rogers,Chen Zhao,Ning Wang,Prashant Rajan,Justin Tomal,Joseph Statz,Ningning Wu,Hue H. Luu,Rex C. Haydon,Tong-Chuan He +22 more
TL;DR: The present review discusses the role of the Wnt signaling pathway in osteogenesis and examines its targeted therapeutic potential and indicates it requires cautious approach due to risks of tumorigenesis.
Journal ArticleDOI
DEER EPR Measurements for Membrane Protein Structures via Bifunctional Spin Labels and Lipodisq Nanoparticles
Indra D. Sahu,Robert M. McCarrick,Kaylee R. Troxel,Rongfu Zhang,Hubbell J. Smith,Megan M. Dunagan,Max S. Swartz,Prashant Rajan,Brett M. Kroncke,Charles R. Sanders,Gary A. Lorigan +10 more
TL;DR: A combination of three recently developed methodologies is employed, bifunctional spin labels, SMA-Lipodisq nanoparticles, and Q band pulsed EPR measurements, to obtain improved signal sensitivity, increased transverse relaxation time, and more accurate and precise distances in DEER measurements on the integral membrane protein KCNE1.
Journal ArticleDOI
Solution Structure of the HIV-1 Exon Splicing Silencer 3.
Jeffrey D. Levengood,Carrie Rollins,Clay H. J. Mishler,Charles A. Johnson,Grace Miner,Prashant Rajan,Brent M. Znosko,Blanton S. Tolbert +7 more
TL;DR: The three-dimensional structure of the exon splicing silencer 3 (ESS3) from HIV-1 has been determined using NMR spectroscopy and shows that the heptaloop adopts a well-organized conformation stabilized primarily by base stacking interactions reminiscent of a U-turn.