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Jongkyeong Chung

Researcher at Seoul National University

Publications -  116
Citations -  14822

Jongkyeong Chung is an academic researcher from Seoul National University. The author has contributed to research in topics: Signal transduction & Kinase. The author has an hindex of 51, co-authored 110 publications receiving 13896 citations. Previous affiliations of Jongkyeong Chung include KAIST & Stanford University.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, +235 more
- 16 Feb 2008 - 
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

TL;DR: The genetic evidence clearly establishes that Parkin and PINK1 act in a common pathway in maintaining mitochondrial integrity and function in both muscles and dopaminergic neurons.
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Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases.

TL;DR: These studies identify a rapamycin-sensitive signaling pathway, argue for a ubiquitous role for FKBPs in signal transduction, indicate that FK506-FKBP-calcineurin complexes do not interfere with pp70S6K signaling, and show that in fibroblasts pp70 S6K, not RSK, is the physiological S6 kinase.
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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

TL;DR: It is reported that PI( 3)K mediates PDGF or insulin receptor signalling to pp70S6k, and PI(3)K-mediated activation of pp70s6k is independent of conventional protein kinase C isoforms.
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STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation.

TL;DR: In vitro and in vivo evidence is provided that the ERK family of mitogen-activated protein (MAP) kinases, but not JNK or p38, specifically phosphorylate STAT3 at serine 727 in response to growth factors.