Bruce A. Bamber

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.

TL;DR: The RPM-1 protein has an RCC1-like guanine nucleotide exchange factor (GEF) domain and a RING-H2 finger and may regulate the spatial arrangement, or restrict the formation, of presynaptic structures.

TL;DR: C. elegans is able to encode a heteromeric GABA receptor with a single locus and the cloned unc-49 possesses an unusual overlapping gene structure, suggesting that the three UNC-49 subunits are coordinately rescued and therefore might coassemble to form a heteromultimeric GABA receptors.

TL;DR: It is shown that GABAA receptors traffic to autophagosomes after endocytic removal from the cell surface and that acetylcholine receptors in the same cells do not traffic toAutophagy can degrade cell-surface receptors and can do so selectively, and a novel function for autophagy is demonstrated in GAB AA receptor degradative trafficking.