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Jeffrey L. Brodsky

Researcher at University of Pittsburgh

Publications -  276
Citations -  20805

Jeffrey L. Brodsky is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Endoplasmic reticulum & Endoplasmic-reticulum-associated protein degradation. The author has an hindex of 71, co-authored 256 publications receiving 18315 citations. Previous affiliations of Jeffrey L. Brodsky include Rice University & University of Washington.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, +235 more
- 16 Feb 2008 - 
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
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One step at a time: endoplasmic reticulum-associated degradation

Shruthi S. Vembar, +1 more
- 12 Nov 2008 - 
TL;DR: The current understanding of each step during ERAD, with emphasis on the factors that catalyse distinct activities is summarized, to highlight the importance of this pathway.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Proteasome-dependent endoplasmic reticulum-associated protein degradation: An unconventional route to a familiar fate

Eric D. Werner, +2 more
- 26 Nov 1996 - 
TL;DR: It is concluded that lumenal ERAD substrates are exported from the yeast ER to the cytoplasm for degradation by the proteasome complex.
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From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.

Gudio Veit, +17 more
- 01 Feb 2016 - 
TL;DR: Establishment of a set of combinatorial categories of the previously defined basic defects in CF alleles will aid the design of even more efficacious therapeutic interventions for CF patients.