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Thomas P. Neufeld

Researcher at University of Minnesota

Publications -  72
Citations -  19962

Thomas P. Neufeld is an academic researcher from University of Minnesota. The author has contributed to research in topics: Autophagy & TOR signaling. The author has an hindex of 45, co-authored 70 publications receiving 17075 citations. Previous affiliations of Thomas P. Neufeld include University of California, Berkeley & Fred Hutchinson Cancer Research Center.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, +235 more
- 16 Feb 2008 - 
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
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ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

TL;DR: A molecular mechanism linking ULK to the pro-autophagic lipid kinase VPS34 is described, whereby the activated ULK1 phosphorylates Beclin-1 on Ser 14, thereby enhancing the activity of the ATG14L-containing V PS34 complexes.
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Regulation of TORC1 by Rag GTPases in nutrient response.

TL;DR: Genetic studies in Drosophila show that Rag GTPases regulate cell growth, autophagy and animal viability during starvation, and establish a function of Rag G TPases in TORC1 activation in response to amino acid signals.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.