scispace - formally typeset
D

David H. Perlmutter

Researcher at Washington University in St. Louis

Publications -  173
Citations -  23907

David H. Perlmutter is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Liver disease & Endoplasmic reticulum. The author has an hindex of 61, co-authored 167 publications receiving 21922 citations. Previous affiliations of David H. Perlmutter include University of Pittsburgh & Baylor College of Medicine.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, +235 more
- 16 Feb 2008 - 
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
Journal ArticleDOI

An Autophagy-Enhancing Drug Promotes Degradation of Mutant α1-Antitrypsin Z and Reduces Hepatic Fibrosis

Tunda Hidvegi, +11 more
- 09 Jul 2010 - 
TL;DR: It is shown that the autophagy-enhancing drug carbamazepine decreased the hepatic load of ATZ and hepatic fibrosis in a mouse model of AT deficiency–associated liver disease, providing a basis for testing CBZ, which has an extensive clinical safety profile, in patients with AT deficiency.
Journal ArticleDOI

Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.

David H. Perlmutter, +3 more
- 01 Nov 1986 - 
TL;DR: The monokine, cachectin/tumor necrosis factor differs from interleukin 1 in primary structure and in recognition by a distinct cellular receptor, and the possibility that recombinant-generated human TNF regulates hepatic acute-phase gene expression was examined.