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Nancy L. Oleinick

Researcher at Case Western Reserve University

Publications -  193
Citations -  17091

Nancy L. Oleinick is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Apoptosis & Photodynamic therapy. The author has an hindex of 57, co-authored 193 publications receiving 15503 citations. Previous affiliations of Nancy L. Oleinick include University Hospitals of Cleveland.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, +235 more
- 16 Feb 2008 - 
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
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The role of apoptosis in response to photodynamic therapy: what, where, why, and how

TL;DR: The purpose of this review is to critically evaluate all of the recently published research on PDT-induced apoptosis, with a focus on studies providing mechanistic insights.
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The Photobiology of Photodynamic Therapy: Cellular Targets and Mechanisms

TL;DR: In spite of generating some responses common to ionizing radiation and other oxidative stresses, PDT is unique in the subcellular localization of damage, the combination of signaling pathways that are activated, and rapid kinetics of the induction of cell death processes.
Journal Article

Photodynamic Therapy Induces Rapid Cell Death by Apoptosis in L5178Y Mouse Lymphoma Cells

TL;DR: The rapidity of the response to PDT suggests that cellular damage produced by PDT can directly activate endonucleolysis and chromatin condensation, thereby by-passing many of the early steps in the signal transduction program which are acted upon by other agents causing apoptosis.