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Xiongwei Zhu

Researcher at Case Western Reserve University

Publications -  411
Citations -  39449

Xiongwei Zhu is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Alzheimer's disease & Oxidative stress. The author has an hindex of 96, co-authored 403 publications receiving 34715 citations. Previous affiliations of Xiongwei Zhu include Autonomous University of Madrid & Wuhan University.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, +235 more
- 16 Feb 2008 - 
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
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Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

Xinglong Wang, +7 more
- 15 Jul 2009 - 
TL;DR: DLP1 overexpression, likely through repopulation of neuronal processes with mitochondria, prevented ADDL-induced synaptic loss, suggesting that abnormal mitochondrial dynamics plays an important role in ADDL -induced synaptic abnormalities.
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Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

Xinglong Wang, +5 more
- 01 Aug 2014 - 
TL;DR: Evidence not only demonstrates the full spectrum of oxidative damage to neuronal macromolecules, but also reveals the occurrence of oxidative events early in the course of the disease and prior to the formation of the pathology, which support an important role of oxidative stress in AD.
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Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

Xinglong Wang, +7 more
- 09 Dec 2008 - 
TL;DR: APP, through amyloid β production, causes an imbalance of mitochondrial fission/fusion that results in mitochondrial fragmentation and abnormal distribution, which contributes to mitochondrial and neuronal dysfunction.