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Zhenyu Yue

Researcher at Icahn School of Medicine at Mount Sinai

Publications -  167
Citations -  33311

Zhenyu Yue is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Autophagy & LRRK2. The author has an hindex of 63, co-authored 155 publications receiving 27299 citations. Previous affiliations of Zhenyu Yue include Central South University & University of Pennsylvania.

Papers
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, +235 more
- 16 Feb 2008 - 
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
Journal ArticleDOI

Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice

Masaaki Komatsu, +26 more
- 14 Dec 2007 - 
TL;DR: The findings highlight the unexpected role of homeostatic level of p62, which is regulated by autophagy, in controlling intracellular inclusion body formation, and indicate that the pathologic process associated with autophagic deficiency is cell-type specific.
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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor.

Zhenyu Yue, +4 more
- 09 Dec 2003 - 
TL;DR: It is demonstrated that beclin 1 is a critical component of mammalian autophagy and a role forAutophagy in tumor suppression is established, and mutations in other genes operating in this pathway may contribute to tumor formation through deregulation of Autophagy.