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Cristina González-Estévez

Researcher at National Institutes of Health

Publications -  19
Citations -  7192

Cristina González-Estévez is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Regeneration (biology) & Planarian. The author has an hindex of 12, co-authored 18 publications receiving 6149 citations. Previous affiliations of Cristina González-Estévez include University of Barcelona & Centro Nacional de Investigaciones Cardiovasculares.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, +235 more
- 16 Feb 2008 - 
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
Journal ArticleDOI

Transgenic planarian lines obtained by electroporation using transposon-derived vectors and an eye-specific GFP marker.

TL;DR: Transgenesis will be an important tool to dissect developmental molecular mechanisms in planarian regeneration, development and stem cell biology, and may also be an entry point to analyze the biology of parasitic Platyhelminthes.
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Gtdap-1 promotes autophagy and is required for planarian remodeling during regeneration and starvation.

TL;DR: The findings suggest that Gtdap-1 is involved in autophagy in planarians, and thatAutophagy plays an essential role in the remodeling of the organism that occurs during regeneration and starvation, providing the necessary energy and building blocks to the neoblasts for cell proliferation and differentiation.
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Decreased neoblast progeny and increased cell death during starvation-induced planarian degrowth

TL;DR: It is concluded that degrowth is a result of cell death decreasing cell numbers and that the dynamics of neoblast self-renewal and differentiation adapt to nutrient conditions to allow maintenance of the neOBlast population during the period of starvation.