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Ettore Bergamini

Researcher at University of Pisa

Publications -  158
Citations -  7198

Ettore Bergamini is an academic researcher from University of Pisa. The author has contributed to research in topics: Insulin & Autophagy. The author has an hindex of 34, co-authored 158 publications receiving 6923 citations. Previous affiliations of Ettore Bergamini include University of Genoa & Yeshiva University.

Papers
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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, +235 more
- 16 Feb 2008 - 
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
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Autophagy and Aging The Importance of Maintaining "Clean" Cells

TL;DR: This work reviews the molecular defects responsible for the malfunctioning of two forms of autophagy - macroautophagy and chaperone-mediated autophage - in old mammals, and highlights general and cell-type specific consequences of dysfunction of the autophagic system with age.
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Prolonged Exposure to Free Fatty Acids Has Cytostatic and Pro-Apoptotic Effects on Human Pancreatic Islets: Evidence that β-Cell Death Is Caspase Mediated, Partially Dependent on Ceramide Pathway, and Bcl-2 Regulated

TL;DR: Extended exposure to FFAs has cytostatic and pro-apoptotic effects on human pancreatic beta-cells, likely to be due to the FFA-induced reduction of intraislet glucose metabolism, and the proapoptosis effects are mostly caspase mediated, partially dependent on ceramide pathway, and possibly Bcl-2 regulated.
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Ageing-related changes in the in vivo function of rat liver macroautophagy and proteolysis.

TL;DR: Data may support the hypothesis that ad libitum feeding accelerates the rate of ageing by raising insulin plasma levels and suppressing autophagy and membrane maintenance, and that calorie restriction may break this vicious circle.
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The role of autophagy in aging: its essential part in the anti-aging mechanism of caloric restriction.

TL;DR: It is concluded that the pharmacologic intensification of autophagy (PISA treatment) has anti‐aging effects and might prove to be a big step toward retardation of aging and prevention of age‐associated diseases in humans.