Willisa Liou

TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.

TL;DR: It is proposed that RME‐4 functions on coated pits and/or vesicles to recruit RAB‐35, which in turn functions in the endosome to promote receptor recycling.

TL;DR: It is found that RME-6 binds specifically to Caenorhabditis elegans RAB-5 in the GDP-bound conformation, and rme-6 mutants have phenotypes that indicate low Rab-5 activity.

TL;DR: Findings reveal a novel EB1-mediated pathway for the secretion of IL-1β, which depends on autophagy-based secretory trafficking through EB1 regulation and is controlled by the 5′-AMP activated protein kinase.

TL;DR: It is proposed that differential compartmentalization of signal transduction components by ciliary proteins is important for the functions of ciliated sensory neurons.