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Calvin K. Yip

Researcher at University of British Columbia

Publications -  80
Citations -  11763

Calvin K. Yip is an academic researcher from University of British Columbia. The author has contributed to research in topics: Autophagy & Protein subunit. The author has an hindex of 32, co-authored 70 publications receiving 8355 citations. Previous affiliations of Calvin K. Yip include University of Victoria & Harvard University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Accurate prediction of protein structures and interactions using a three-track neural network

Minkyung Baek, +33 more
- 20 Aug 2021 - 
TL;DR: In this article, a three-track network is proposed to combine information at the one-dimensional (1D) sequence level, the 2D distance map level, and the 3D coordinate level.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Structure of the Human mTOR Complex I and Its Implications for Rapamycin Inhibition

Calvin K. Yip, +5 more
- 11 Jun 2010 - 
TL;DR: In this paper, the authors determined the 3D structure of the fully assembled human mTORC1 by cryo-electron microscopy (cryo-EM) and showed that mTOR is an obligate dimer with an overall rhomboid shape and a central cavity.

Structure of the human mTOR Complex I and its implications for rapamycin inhibition

Calvin K. Yip, +5 more
TL;DR: This work proposes a model in which rapamycin inhibits mTORC1-mediated phosphorylation of 4E-BP1 and S6K1 through different mechanisms, and determines the three-dimensional structure of the fully assembled human m TORC1 by cryo-electron microscopy.