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Andrey S. Tsvetkov

Researcher at University of Texas at Austin

Publications -  38
Citations -  8249

Andrey S. Tsvetkov is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Autophagy & Neurodegeneration. The author has an hindex of 21, co-authored 33 publications receiving 6643 citations. Previous affiliations of Andrey S. Tsvetkov include University of Texas Health Science Center at Houston & University of California, San Francisco.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

Sami J. Barmada, +12 more
- 01 Aug 2014 - 
TL;DR: It is shown that individual neurons vary in their ability to clear TDP 43 and are exquisitely sensitive to TDP43 levels, and that autophagy induction mitigates neurodegeneration by acting directly on TDP44 clearance.
Journal ArticleDOI

A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model.

Andrey S. Tsvetkov, +5 more
- 28 Sep 2010 - 
TL;DR: A structure/activity analysis with structurally similar compounds approved by the US Food and Drug Administration revealed a defined pharmacophore for inducing neuronal autophagy, an N10-substituted phenoxazine that was neuroprotective and decreased the accumulation of diffuse and aggregated misfolded protein in neurons.
Journal ArticleDOI

Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration

Andrey S. Tsvetkov, +6 more
- 01 Sep 2013 - 
TL;DR: It is found that neuronal longevity is predicted by the mean lifetime of huntingtin, as cortical neurons cleared mutant huntingtin faster and lived longer than striatal neurons, suggesting cell type-specific differences in turnover capacity may contribute to cellular susceptibility to toxic proteins.