Paul G. Thomes

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: This review summarizes the current knowledge about the role and implications of autophagy in alcohol-induced liver disease and suggests that survival and preservation of cellular integrity at the expense of inadequately folded proteins and damaged high-energy generating intracellular organelles are prominent targets of autophile in pathological conditions.

TL;DR: The findings suggest that the effect of acute EtOH gavage on hepatic autophagy differs significantly from that after chronic EtOH feeding, and each regimen distinctly affects TFEB localization, which in turn, regulates hepatic Autophagy and lysosome biogenesis.

TL;DR: Fucoidan provide cardioprotection against isoproterenol induced myocardial infarction in rats and improved the antioxidant defence system in treated animals and considerably reduced the oxidative stress exerted by isop roterenol.