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Simon Wilkinson

Researcher at University of Edinburgh

Publications -  93
Citations -  15271

Simon Wilkinson is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 30, co-authored 90 publications receiving 12472 citations. Previous affiliations of Simon Wilkinson include Newcastle University & University of Newcastle.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis

TL;DR: DRAM (damage-regulated autophagy modulator), a p53 target gene encoding a lysosomal protein that induces macroautophagy, is described as an effector of p53-mediated death and its relationship to p53 function and damage-induced programmed cell death is highlighted.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion.

TL;DR: It is shown that contractility necessary for elongated morphology and invasion can be generated by Cdc42–MRCK signalling, which mediates myosin-dependent cell motility and highlight convergence between Rho and CDC42 signalling.