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Arthi Kanthasamy

Researcher at Iowa State University

Publications -  139
Citations -  13092

Arthi Kanthasamy is an academic researcher from Iowa State University. The author has contributed to research in topics: Dopaminergic & Neurodegeneration. The author has an hindex of 51, co-authored 132 publications receiving 10012 citations. Previous affiliations of Arthi Kanthasamy include University of California, Irvine.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: implication for cell death.

TL;DR: It is concluded that glutamate induces concurrent generation of NO and ROS by activation of both NMDA receptors and non‐NMDA receptors through a Ca2+‐mediated process and it is proposed that simultaneous generation ofNO and ROS results in formation of peroxynitrite, which initiates the cellular damage.
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Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes.

TL;DR: In this review, the recent developments in mitochondria-targeted antioxidants and their potential beneficial effects as a therapy for ameliorating mitochondrial dysfunction in Parkinson's disease are discussed.
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Dieldrin-induced neurotoxicity: relevance to Parkinson's disease pathogenesis.

TL;DR: Various neurotoxic studies conducted in both cell culture and animals models following dieldrin exposure are summarized and discusses their relevance to key pathological mechanisms associated with nigral dopaminergic degeneration including oxidative stress, mitochondrial dysfunction, protein aggregation, and apoptosis.