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Steven Finkbeiner

Researcher at University of California, San Francisco

Publications -  194
Citations -  37280

Steven Finkbeiner is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Neurodegeneration & Huntingtin. The author has an hindex of 69, co-authored 174 publications receiving 31703 citations. Previous affiliations of Steven Finkbeiner include Boston Children's Hospital & University of California.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

Montserrat Arrasate, +4 more
- 14 Oct 2004 - 
TL;DR: It is shown, by survival analysis, that neurons die in a time-independent fashion but one that is dependent on mutant huntingtin dose and polyglutamine expansion; many neurons die without forming an inclusion body.
Journal ArticleDOI

Glutamate induces calcium waves in cultured astrocytes: long-range glial signaling

Ann H. Cornell-Bell, +3 more
- 26 Jan 1990 - 
TL;DR: It is reported that cultured hippocampal astrocytes can respond to glutamate with a prompt and oscillatory elevation of cytoplasmic free calcium, visible through use of the fluorescent calcium indicator fluo-3.
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Huntingtin Acts in the Nucleus to Induce Apoptosis but Death Does Not Correlate with the Formation of Intranuclear Inclusions

Frédéric Saudou, +5 more
- 02 Oct 1998 - 
TL;DR: It is suggested that mutant huntingtin acts within the nucleus to induce neurodegeneration, however, intranuclear inclusions may reflect a cellular mechanism to protect against huntingtin-induced cell death.