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Ignacio Vega-Naredo

Researcher at University of Oviedo

Publications -  59
Citations -  7992

Ignacio Vega-Naredo is an academic researcher from University of Oviedo. The author has contributed to research in topics: Oxidative stress & Melatonin. The author has an hindex of 24, co-authored 55 publications receiving 6466 citations. Previous affiliations of Ignacio Vega-Naredo include University of Zaragoza & International Sleep Products Association.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Differential inflammatory responses in aging and disease: TNF-α and IL-6 as possible biomarkers

TL;DR: TNF-alpha, the first element in the cytokine cascade, was significantly increased in the aged population, implying that aging is accompanied by a gradual increase in this inflammatory biomarker, and IL-6 was not associated with aging, but it was highly elevated under hypoxia conditions in elderly subjects.
Journal ArticleDOI

Therapeutic potential of melatonin related to its role as an autophagy regulator: A review

TL;DR: This review focuses on major physiological changes such as aging and essential pathologies including cancer, neurodegenerative diseases, viral infections and obesity, and document the essential role of melatonin in the regulation of autophagy in each of these different situations.
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Favorable effects of a prolonged treatment with melatonin on the level of oxidative damage and neurodegeneration in senescence-accelerated mice.

TL;DR: Treatment with melatonin in SAMP8 and SAMR1 mice reduced the neurodegenerative changes with an increase of ROR‐α1 levels without an apparent influence in the levels of MT‐1 receptor, confirming the direct role of oxidative stress in the aging process.