Gopal Chakrabarti

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: It is demonstrated that miR-17-5p directly binds to the 3′-UTR of beclin 1 gene, one of the most important autophagy modulator, and indicated that paclitaxel resistance of lung cancer is associated with downregulation of miR -17- 5p expression which might cause upregulation of BECN1 expression.

TL;DR: This first observation of nanoparticles-induced protein's conformational change-based aggregation of the tubulin-MT system is of high importance, and would be useful in the understanding of cancer therapeutics and safety of nanomaterials.

TL;DR: It was demonstrated that anti-apoptotic protein Bcl-2 was directly targeted miR-16 in paclitaxel resistant lung cancer cells and the combined overexpression of mi R-16 and miR -17 and subsequent pac litaxel treatment greatly sensitized paclitAXel resistant Lung cancer cells to paclitaxeel by inducing apoptosis via caspase-3 mediated pathway.