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Hirotaka Watada

Hirotaka Watada

Researcher at Juntendo University

Publications - 517

Citations - 28106

Hirotaka Watada is an academic researcher from Juntendo University. The author has contributed to research in topics: Diabetes mellitus & Type 2 diabetes. The author has an hindex of 67, co-authored 460 publications receiving 23479 citations. Previous affiliations of Hirotaka Watada include Osaka University & University of California, San Francisco.

Papers

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

- 21 Jan 2016 -

Autophagy

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TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

- 01 Apr 2012 -

Autophagy

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TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

...read moreread less

Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

- 08 Feb 2021 -

Autophagy

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TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

...read moreread less

Journal ArticleDOI

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

Chie Ebato,Toyoyoshi Uchida,Masayuki Arakawa,Masaaki Komatsu,Masaaki Komatsu,Masaaki Komatsu,Takashi Ueno,Koji Komiya,Kosuke Azuma,Takahisa Hirose,Keiji Tanaka,Eiki Kominami,Ryuzo Kawamori,Yoshio Fujitani,Hirotaka Watada +14 moreJuntendo University,National Presto Industries,Institute of Medical Science

- 08 Oct 2008 -

Cell Metabolism

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TL;DR: Upregulation of autophagosome formation in pancreatic beta cells in diabetic db/db and in nondiabetic high-fat-fed C57BL/6 mice suggests that basal autophagy is important for maintenance of normal islet architecture and function.

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Journal ArticleDOI

Serotonin regulates pancreatic beta cell mass during pregnancy.

Hail Kim,Yukiko Toyofuku,Francis C. Lynn,Francis C. Lynn,Eric W Chak,Toyoyoshi Uchida,Hiroki Mizukami,Yoshio Fujitani,Ryuzo Kawamori,Takeshi Miyatsuka,Yasuhiro Kosaka,Katherine Yang,Gerard Honig,Marieke van der Hart,Nina Kishimoto,Juehu Wang,Soroku Yagihashi,Laurence H. Tecott,Hirotaka Watada,Michael S. German +19 moreUniversity of California, San Francisco,Juntendo University,University of British Columbia,Hirosaki University

- 01 Jul 2010 -

Nature Medicine

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TL;DR: An integrated signaling pathway linking beta cell mass to anticipated insulin need during pregnancy is revealed and modulators of this pathway, including medications and diet, may affect the risk of gestational diabetes.

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