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Anne Hamacher-Brady

Researcher at Johns Hopkins University

Publications -  43
Citations -  10918

Anne Hamacher-Brady is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Autophagy & Mitochondrion. The author has an hindex of 28, co-authored 42 publications receiving 8860 citations. Previous affiliations of Anne Hamacher-Brady include San Diego State University & German Cancer Research Center.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy.

Anne Hamacher-Brady, +7 more
- 01 Jan 2007 - 
TL;DR: The results suggest that Bnip3 contributes to I/R injury which triggers a protective stress response with upregulation of autophagy and removal of damaged mitochondria.
Journal ArticleDOI

Enhancing Macroautophagy Protects against Ischemia/Reperfusion Injury in Cardiac Myocytes

Anne Hamacher-Brady, +2 more
- 06 Oct 2006 - 
TL;DR: It is found that autophagic flux is impaired at the level of both induction and degradation and that enhancing autophagy constitutes a powerful and previously uncharacterized protective mechanism against I/R injury to the heart cell.
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Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells.

Nils Eling, +4 more
TL;DR: It is demonstrated that ART specifically induced ROS- and lysosomal iron-dependent cell death in PDAC cell lines, and activation of ferroptosis is an effective, novel pathway for killing PDAC cells.