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Shouqing Luo

Researcher at University of Plymouth

Publications -  52
Citations -  13730

Shouqing Luo is an academic researcher from University of Plymouth. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 29, co-authored 50 publications receiving 11554 citations. Previous affiliations of Shouqing Luo include Peking Union Medical College & University of Cambridge.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.

Brinda Ravikumar, +10 more
- 16 May 2004 - 
TL;DR: This work shows that mammalian target of rapamycin (mTOR) is sequestered in polyglutamine aggregates in cell models, transgenic mice and human brains, and provides proof-of-principle for the potential of inducing autophagy to treat Huntington disease.
Journal ArticleDOI

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

Brinda Ravikumar, +18 more
- 01 Oct 2010 - 
TL;DR: This review focuses on mammalian autophagy, and an overview of the understanding of its machinery and the signaling cascades that regulate it is given, and the possibility of autophagic upregulation as a therapeutic approach for various conditions is considered.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL.

Shouqing Luo, +1 more
- 01 Feb 2010 - 
TL;DR: It is shown that apoptosis can suppress autophagy, as a non-cleavable Beclin 1 mutant restored autophagic in cells overexpressing Bax.