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Elena Ortona

Researcher at Istituto Superiore di Sanità

Publications -  148
Citations -  11898

Elena Ortona is an academic researcher from Istituto Superiore di Sanità. The author has contributed to research in topics: Echinococcus granulosus & Antigen. The author has an hindex of 45, co-authored 144 publications receiving 9782 citations. Previous affiliations of Elena Ortona include Catholic University of the Sacred Heart & Wake Forest University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Sex-based differences in autoimmune diseases.

TL;DR: Possible mechanisms for sex specific differences in autoimmunity with a special focus on three paradigmatic diseases: systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis are discussed.
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Anti-β2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor α and tissue factor by signal transduction pathways involving lipid rafts

TL;DR: New insight is provided into the pathogenesis of APS and anti-β2GPI antibodies react with their target antigen, likely in association with annexin A2 and TLR-4, in lipid rafts in the monocyte plasma membrane, improving the knowledge of valuable therapeutic targets.
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Modulation of Human Immune Response by Echinococcus granulosus Antigen B and Its Possible Role in Evading Host Defenses

TL;DR: Findings confirm that AgB plays a role in the escape from early immunity by inhibiting PMN chemotaxis and add new information on the host-parasite relationship, suggesting thatAgB exploits the activation of T helper cells by eliciting a nonprotective Th2 cell response.