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Congfeng Xu

Researcher at Shanghai Jiao Tong University

Publications -  29
Citations -  7226

Congfeng Xu is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Autophagy & Receptor. The author has an hindex of 16, co-authored 25 publications receiving 5744 citations. Previous affiliations of Congfeng Xu include Sanford-Burnham Institute for Medical Research & Discovery Institute.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

A five-amino-acid motif in the undefined region of the TLR8 ectodomain is required for species-specific ligand recognition.

TL;DR: Interestingly, distinct from humanTLR8, mouse TLR8 was not responsive to ligand stimulation in the absence of polyT-oligodeoxynucleotides (polyT-ODN), suggesting the molecular basis for this distinct ligand recognition is still unclear.
Journal ArticleDOI

Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.

TL;DR: It is demonstrated that inflammatory microenvironment-induced autophagy downregulates the immunosuppressive function of MSCs and would provide a novel strategy to improve MSC-based immunotherapy.
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Functional interaction of heat shock protein 90 and Beclin 1 modulates Toll-like receptor-mediated autophagy

TL;DR: It is shown that Hsp90 forms a complex with Beclin 1 through an evolutionarily conserved domain to maintain the stability of BeClin 1, and plays a novel role in TLR‐mediated autophagy.