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J. Lindsay Whitton

Researcher at Scripps Research Institute

Publications -  123
Citations -  19330

J. Lindsay Whitton is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Cytotoxic T cell & Virus. The author has an hindex of 54, co-authored 123 publications receiving 16699 citations. Previous affiliations of J. Lindsay Whitton include Torrey Pines Institute for Molecular Studies & Scripps Health.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Molecular Mimicry, Bystander Activation, or Viral Persistence: Infections and Autoimmune Disease

TL;DR: Mechanisms used to explain the association of autoimmunity and virus infection are molecular mimicry, bystander activation, and viral persistance, which are discussed in the context of multiple sclerosis, myocarditis, and diabetes.
Journal ArticleDOI

Functional avidity maturation of CD8 + T cells without selection of higher affinity TCR

TL;DR: It is shown that T cell responsiveness to peptide (termed “functional avidity”) increased>50-fold during the early stages of viral infection, indicating that T cells, like B cells, undergo extensive functional maturation in vivo.