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Jon D. Lane

Researcher at University of Bristol

Publications -  67
Citations -  14007

Jon D. Lane is an academic researcher from University of Bristol. The author has contributed to research in topics: Autophagy & Autophagosome. The author has an hindex of 31, co-authored 62 publications receiving 11370 citations. Previous affiliations of Jon D. Lane include University of Manchester & University of Minnesota.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Nanoparticles can cause DNA damage across a cellular barrier

Gevdeep Bhabra, +16 more
- 01 Dec 2009 - 
TL;DR: It is shown that cobalt-chromium nanoparticles (29.5 +/- 6.3 nm in diameter) can damage human fibroblast cells across an intact cellular barrier without having to cross the barrier.
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Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis

Virginie M S Betin, +1 more
- 15 Jul 2009 - 
TL;DR: Data suggest that Atg4D is an autophagy regulator that links mitochondrial dysfunction with apoptosis, and also acquires affinity for damaged mitochondria in cells treated with hydrogen peroxide.